Explore ANTXR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
| Target ID |
GM-MP0068
|
| Target Name |
ANTXR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
84168
|
| Gene ID |
100061334 (Equus caballus), 100425392 (Macaca mulatta), 101092930 (Felis catus), 362393 (Rattus norvegicus)
612601 (Canis lupus familiaris), 616010 (Bos taurus), 69538 (Mus musculus), 84168 (Homo sapiens)
|
| Target Alternative Names |
2310008J16Rik,2810405N18Rik,ANTXR1,ATR,Anthrax toxin receptor 1,Antrx1,Antxr1,GAPO,TEM8,Tem8,Tumor endothelial marker 8
|
| Uniprot Accession |
Q0PMD2,Q9CZ52,Q9H6X2
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
NOD-like receptor signaling pathway
|
| Gene Ensembl |
ENSECAG00000007023, ENSMMUG00000014244, ENSCAFG00845024244, ENSBTAG00000007808, ENSMUSG00000033420, ENSG00000169604
|
Pre-made viral vector of ANTXR1 cDNA Clones/ORF Plasmid
ANTXR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84168 | Pre-made Human ANTXR1/ATR/GAPO siRNA oligo Duplex | 84168 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362393 | Pre-made Rat Antxr1 siRNA oligo Duplex | 362393 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo69538 | Pre-made Mouse Antxr1/Tem8/Antrx1 siRNA oligo Duplex | 69538 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100425392 | Pre-made Cynomolgus/Rhesus macaque ANTXR1 siRNA oligo Duplex | 100425392 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092930 | Pre-made Cat/Feline ANTXR1 siRNA oligo Duplex | 101092930 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612601 | Pre-made Dog/Canine ANTXR1 siRNA oligo Duplex | 612601 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616010 | Pre-made Bovines/Cattle ANTXR1 siRNA oligo Duplex | 616010 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061334 | Pre-made Equine/Horse ANTXR1 siRNA oligo Duplex | 100061334 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ANTXR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0068-Ab | Human | Anti-Human ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0068-Ab | Rat | Anti-Rat ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0068-Ab | Mouse | Anti-Mouse ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0068-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0068-Ab | Cat/Feline | Anti-Cat/Feline ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0068-Ab | Dog/Canine | Anti-Dog/Canine ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0068-Ab | Bovines/Cattle | Anti-Bovines/Cattle ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0068-Ab | Equine/Horse | Anti-Equine/Horse ANTXR1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ANTXR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0068-Ag | Human | Human ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0068-Ag | Rat | Rat ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0068-Ag | Mouse | Mouse ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0068-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0068-Ag | Cat/Feline | Cat/Feline ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0068-Ag | Dog/Canine | Dog/Canine ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0068-Ag | Bovines/Cattle | Bovines/Cattle ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0068-Ag | Equine/Horse | Equine/Horse ANTXR1 VLP (virus-like particle) | HEK293 | Products Developing |
