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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]
| Target ID |
GM-MP0053
|
| Target Name |
ALPI
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
248
|
| Gene ID |
101083873 (Felis catus), 248 (Homo sapiens), 403736 (Canis lupus familiaris), 721052 (Macaca mulatta) 76768 (Mus musculus)
|
| Target Alternative Names |
2010001C14Rik,ALPI,ALPP,Akp6,Alpi,IAP,Intestinal alkaline phosphatase,Intestinal-type alkaline phosphatase,gIAP
|
| Uniprot Accession |
P09923
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Acute kidney failure
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSG00000163295, ENSCAFG00845025234, ENSMMUG00000006985, ENSMUSG00000079440
|
Pre-made viral vector of ALPI cDNA Clones/ORF Plasmid
ALPI siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo248 | Pre-made Human ALPI/IAP siRNA oligo Duplex | 248 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo76768 | Pre-made Mouse Alpi/Akp6/gIAP siRNA oligo Duplex | 76768 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721052 | Pre-made Cynomolgus/Rhesus macaque ALPI siRNA oligo Duplex | 721052 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083873 | Pre-made Cat/Feline ALPI siRNA oligo Duplex | 101083873 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403736 | Pre-made Dog/Canine ALPI/ALPP siRNA oligo Duplex | 403736 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
ALPI antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0053-Ab | Human | Anti-Human ALPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0053-Ab | Mouse | Anti-Mouse ALPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0053-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ALPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0053-Ab | Cat/Feline | Anti-Cat/Feline ALPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0053-Ab | Dog/Canine | Anti-Dog/Canine ALPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ALPI VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0053-Ag | Human | Human ALPI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0053-Ag | Mouse | Mouse ALPI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0053-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ALPI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0053-Ag | Cat/Feline | Cat/Feline ALPI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0053-Ag | Dog/Canine | Dog/Canine ALPI VLP (virus-like particle) | HEK293 | Products Developing |