Explore ADAM22 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]
| Target ID |
GM-MP0036
|
| Target Name |
ADAM22
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
53616
|
| Gene ID |
100050380 (Equus caballus), 101098366 (Felis catus), 11496 (Mus musculus), 482286 (Canis lupus familiaris)
523645 (Bos taurus), 53616 (Homo sapiens), 57033 (Rattus norvegicus), 705350 (Macaca mulatta)
|
| Target Alternative Names |
2900022I03Rik,ADAM 22,ADAM22,Adam22,DEE61,Disintegrin and metalloproteinase domain-containing protein 22,EIEE61,MDC2,Metalloproteinase-disintegrin ADAM22-3,Metalloproteinase-like,and cysteine-rich protein 2,disintegrin-like
|
| Uniprot Accession |
Q9R1V6,Q9P0K1
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSECAG00000019027, ENSMUSG00000040537, ENSCAFG00845009211, ENSBTAG00000007136, ENSG00000008277, ENSMMUG00000022695
|
ADAM22 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo53616 | Pre-made Human ADAM22/MDC2/DEE61 siRNA oligo Duplex | 53616 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo57033 | Pre-made Rat Adam22/MDC2 siRNA oligo Duplex | 57033 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11496 | Pre-made Mouse Adam22/MDC2/2900022I03Rik siRNA oligo Duplex | 11496 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705350 | Pre-made Cynomolgus/Rhesus macaque ADAM22 siRNA oligo Duplex | 705350 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098366 | Pre-made Cat/Feline ADAM22 siRNA oligo Duplex | 101098366 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482286 | Pre-made Dog/Canine ADAM22 siRNA oligo Duplex | 482286 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523645 | Pre-made Bovines/Cattle ADAM22 siRNA oligo Duplex | 523645 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050380 | Pre-made Equine/Horse ADAM22 siRNA oligo Duplex | 100050380 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADAM22 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0036-Ab | Human | Anti-Human ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0036-Ab | Rat | Anti-Rat ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0036-Ab | Mouse | Anti-Mouse ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0036-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0036-Ab | Cat/Feline | Anti-Cat/Feline ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0036-Ab | Dog/Canine | Anti-Dog/Canine ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0036-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0036-Ab | Equine/Horse | Anti-Equine/Horse ADAM22 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ADAM22 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0036-Ag | Human | Human ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0036-Ag | Rat | Rat ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0036-Ag | Mouse | Mouse ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0036-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0036-Ag | Cat/Feline | Cat/Feline ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0036-Ag | Dog/Canine | Dog/Canine ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0036-Ag | Bovines/Cattle | Bovines/Cattle ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0036-Ag | Equine/Horse | Equine/Horse ADAM22 VLP (virus-like particle) | HEK293 | Products Developing |
