Explore ACVR1C gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
| Target ID |
GM-MP0029
|
| Target Name |
ACVR1C
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
130399
|
| Gene ID |
100059573 (Equus caballus), 101091037 (Felis catus), 130399 (Homo sapiens), 245921 (Rattus norvegicus)
269275 (Mus musculus), 488361 (Canis lupus familiaris), 536380 (Bos taurus), 697826 (Macaca mulatta)
|
| Target Alternative Names |
ACVR1C,Acvr1c,ALK7,ACVRLK7,Alk7,Alk-7,habrec1,ACTR-IC,C230097P10
|
| Uniprot Accession |
Q8NER5,P70539,Q8K348
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease |
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells
|
| Gene Ensembl |
ENSECAG00000019682, ENSG00000123612, ENSMUSG00000026834, ENSCAFG00845026018, ENSBTAG00000019337, ENSMMUG00000003707
|
| Target Classification |
Cytokine Receptor
|
ACVR1C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo130399 | Pre-made Human ACVR1C/ALK7/ACVRLK7 siRNA oligo Duplex | 130399 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo245921 | Pre-made Rat Acvr1c/Alk7/Alk-7 siRNA oligo Duplex | 245921 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo269275 | Pre-made Mouse Acvr1c/ALK7/Alk-7 siRNA oligo Duplex | 269275 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697826 | Pre-made Cynomolgus/Rhesus macaque ACVR1C siRNA oligo Duplex | 697826 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091037 | Pre-made Cat/Feline ACVR1C siRNA oligo Duplex | 101091037 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488361 | Pre-made Dog/Canine ACVR1C siRNA oligo Duplex | 488361 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536380 | Pre-made Bovines/Cattle ACVR1C siRNA oligo Duplex | 536380 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059573 | Pre-made Equine/Horse ACVR1C siRNA oligo Duplex | 100059573 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ACVR1C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0029-Ab | Human | Anti-Human ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0029-Ab | Rat | Anti-Rat ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0029-Ab | Mouse | Anti-Mouse ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0029-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0029-Ab | Cat/Feline | Anti-Cat/Feline ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0029-Ab | Dog/Canine | Anti-Dog/Canine ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0029-Ab | Bovines/Cattle | Anti-Bovines/Cattle ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0029-Ab | Equine/Horse | Anti-Equine/Horse ACVR1C monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
ACVR1C VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0029-Ag | Human | Human ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0029-Ag | Rat | Rat ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0029-Ag | Mouse | Mouse ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0029-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0029-Ag | Cat/Feline | Cat/Feline ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0029-Ag | Dog/Canine | Dog/Canine ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0029-Ag | Bovines/Cattle | Bovines/Cattle ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0029-Ag | Equine/Horse | Equine/Horse ACVR1C VLP (virus-like particle) | HEK293 | Products Developing |
