Explore Alpha Actinin/ACTN1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0027
|
| Target Name |
Alpha Actinin/ACTN1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
87
|
| Gene ID |
100053070 (Equus caballus), 101097986 (Felis catus), 109711 (Mus musculus), 480369 (Canis lupus familiaris)
524770 (Bos taurus), 711994 (Macaca mulatta), 81634 (Rattus norvegicus), 87 (Homo sapiens)
|
| Target Alternative Names |
3110023F10Rik,ACTN1,Actn1,Actn1a,Alpha Actinin,Alpha-actinin cytoskeletal isoform,Alpha-actinin-1,BDPLT15,F-actin cross-linking protein,Non-muscle alpha-actinin-1
|
| Uniprot Accession |
Q7TPR4,Q3B7N2,Q9Z1P2,P12814
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Focal adhesion, Adherens junction, Tight junction, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Amoebiasis
|
| Gene Ensembl |
ENSECAG00000019476, ENSMUSG00000015143, ENSCAFG00845003783, ENSBTAG00000018255, ENSMMUG00000010767, ENSG00000072110
|
| Target Classification |
|
Alpha Actinin/ACTN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo87 | Pre-made Human ACTN1/BDPLT15 siRNA oligo Duplex | 87 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81634 | Pre-made Rat Actn1 siRNA oligo Duplex | 81634 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109711 | Pre-made Mouse Actn1/Actn1a/3110023F10Rik siRNA oligo Duplex | 109711 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711994 | Pre-made Cynomolgus/Rhesus macaque ACTN1 siRNA oligo Duplex | 711994 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097986 | Pre-made Cat/Feline ACTN1 siRNA oligo Duplex | 101097986 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480369 | Pre-made Dog/Canine ACTN1 siRNA oligo Duplex | 480369 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524770 | Pre-made Bovines/Cattle ACTN1 siRNA oligo Duplex | 524770 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053070 | Pre-made Equine/Horse ACTN1 siRNA oligo Duplex | 100053070 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Alpha Actinin/ACTN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0027-Ab | Human | Anti-Human Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0027-Ab | Rat | Anti-Rat Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0027-Ab | Mouse | Anti-Mouse Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0027-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0027-Ab | Cat/Feline | Anti-Cat/Feline Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0027-Ab | Dog/Canine | Anti-Dog/Canine Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0027-Ab | Bovines/Cattle | Anti-Bovines/Cattle Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0027-Ab | Equine/Horse | Anti-Equine/Horse Alpha Actinin/ACTN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Alpha Actinin/ACTN1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0027-Ag | Human | Human Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0027-Ag | Rat | Rat Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0027-Ag | Mouse | Mouse Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0027-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0027-Ag | Cat/Feline | Cat/Feline Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0027-Ag | Dog/Canine | Dog/Canine Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0027-Ag | Bovines/Cattle | Bovines/Cattle Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0027-Ag | Equine/Horse | Equine/Horse Alpha Actinin/ACTN1 VLP (virus-like particle) | HEK293 | Products Developing |
