Explore ACSL3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0022
|
| Target Name |
ACSL3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2181
|
| Gene ID |
100056656 (Equus caballus), 100138312 (Bos taurus), 101081999 (Felis catus), 114024 (Rattus norvegicus)
2181 (Homo sapiens), 478927 (Canis lupus familiaris), 706050 (Macaca mulatta), 74205 (Mus musculus)
|
| Target Alternative Names |
2610510B12Rik,ACS3,ACSL3,Acs3,Acsl3,Arachidonate--CoA ligase,FACL3,Facl3,Fatty acid CoA ligase Acsl3,LACS 3,LACS3,Long-chain acyl-CoA synthetase 3 (LACS 3),Long-chain-fatty-acid--CoA ligase 3,Medium-chain acyl-CoA ligase Acsl3,PRO2194,Pro2194
|
| Uniprot Accession |
Q63151,O95573,Q9CZW4
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
Metabolic pathways, PPAR signaling pathway, Ferroptosis, Adipocytokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000010765, ENSBTAG00000017258, ENSG00000123983, ENSCAFG00845017709, ENSMMUG00000005393, ENSMUSG00000032883
|
Pre-made viral vector of ACSL3 cDNA Clones/ORF Plasmid
ACSL3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2181 | Pre-made Human ACSL3/ACS3/FACL3 siRNA oligo Duplex | 2181 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114024 | Pre-made Rat Acsl3/Acs3/Facl3 siRNA oligo Duplex | 114024 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74205 | Pre-made Mouse Acsl3/Acs3/Facl3 siRNA oligo Duplex | 74205 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706050 | Pre-made Cynomolgus/Rhesus macaque ACSL3 siRNA oligo Duplex | 706050 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081999 | Pre-made Cat/Feline ACSL3 siRNA oligo Duplex | 101081999 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478927 | Pre-made Dog/Canine ACSL3 siRNA oligo Duplex | 478927 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100138312 | Pre-made Bovines/Cattle ACSL3 siRNA oligo Duplex | 100138312 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056656 | Pre-made Equine/Horse ACSL3 siRNA oligo Duplex | 100056656 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ACSL3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0022-Ab | Human | Anti-Human ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0022-Ab | Rat | Anti-Rat ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0022-Ab | Mouse | Anti-Mouse ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0022-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0022-Ab | Cat/Feline | Anti-Cat/Feline ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0022-Ab | Dog/Canine | Anti-Dog/Canine ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0022-Ab | Bovines/Cattle | Anti-Bovines/Cattle ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0022-Ab | Equine/Horse | Anti-Equine/Horse ACSL3 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ACSL3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0022-Ag | Human | Human ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0022-Ag | Rat | Rat ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0022-Ag | Mouse | Mouse ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0022-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0022-Ag | Cat/Feline | Cat/Feline ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0022-Ag | Dog/Canine | Dog/Canine ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0022-Ag | Bovines/Cattle | Bovines/Cattle ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0022-Ag | Equine/Horse | Equine/Horse ACSL3 VLP (virus-like particle) | HEK293 | Products Developing |
