Explore XAF1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
| Target ID |
GM-IP9797
|
| Target Name |
XAF1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
54739
|
| Gene ID |
100072746 (Equus caballus), 119871834 (Canis lupus familiaris), 327959 (Mus musculus), 509740 (Bos taurus) 54739 (Homo sapiens), 679600 (Rattus norvegicus), 713425 (Macaca mulatta)
|
| Target Alternative Names |
BIRC4-binding protein,BIRC4BP,Fbox39,HSXIAPAF1,XAF1,XIAP-associated factor 1,XIAPAF1,Xaf1
|
| Uniprot Accession |
Q5NBU8,Q58DH1,Q6GPH4
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSCAFG00845002091, ENSMUSG00000040483, ENSBTAG00000011343, ENSG00000132530, ENSMMUG00000009602
|
Pre-made viral vector of XAF1 cDNA Clones/ORF Plasmid
XAF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54739 | Pre-made Human XAF1/BIRC4BP/XIAPAF1 siRNA oligo Duplex | 54739 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo679600 | Pre-made Rat Xaf1 siRNA oligo Duplex | 679600 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo327959 | Pre-made Mouse Xaf1/Fbox39 siRNA oligo Duplex | 327959 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713425 | Pre-made Cynomolgus/Rhesus macaque XAF1 siRNA oligo Duplex | 713425 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119871834 | Pre-made Dog/Canine XAF1 siRNA oligo Duplex | 119871834 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509740 | Pre-made Bovines/Cattle XAF1/BIRC4BP/HSXIAPAF1 siRNA oligo Duplex | 509740 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072746 | Pre-made Equine/Horse XAF1 siRNA oligo Duplex | 100072746 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
XAF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9797-Ab | Human | Anti-Human XAF1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9797-Ab | Rat | Anti-Rat XAF1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9797-Ab | Mouse | Anti-Mouse XAF1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9797-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque XAF1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9797-Ab | Dog/Canine | Anti-Dog/Canine XAF1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9797-Ab | Bovines/Cattle | Anti-Bovines/Cattle XAF1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9797-Ab | Equine/Horse | Anti-Equine/Horse XAF1 monoclonal antibody | mab | | Detail |
XAF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9797-Ag | Human | Human XAF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9797-Ag | Rat | Rat XAF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9797-Ag | Mouse | Mouse XAF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9797-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque XAF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9797-Ag | Dog/Canine | Dog/Canine XAF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9797-Ag | Bovines/Cattle | Bovines/Cattle XAF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9797-Ag | Equine/Horse | Equine/Horse XAF1 recombinant protein | Mammalian cell | Detail |