Explore LARS/LARS1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015]
| Target ID |
GM-IP9459
|
| Target Name |
LARS/LARS1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
51520
|
| Gene ID |
100061092 (Equus caballus), 101083060 (Felis catus), 107045 (Mus musculus), 291624 (Rattus norvegicus)
478051 (Canis lupus familiaris), 509429 (Bos taurus), 51520 (Homo sapiens), 706792 (Macaca mulatta)
|
| Target Alternative Names |
2310045K21Rik,3110009L02Rik,HSPC192,ILFS1,LARS,LARS1,LEURS,LEUS,LFIS,LRS,Lars,Lars1,Leucine--tRNA ligase,Leucyl-tRNA synthetase (LeuRS,PIG44,RNTLS,cLRS,cLRS),cytoplasmic,hr025Cl,leuRS
|
| Uniprot Accession |
Q8BMJ2,Q9P2J5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000008963, ENSMUSG00000024493, ENSCAFG00845020164, ENSBTAG00000006765, ENSG00000133706, ENSMMUG00000029787
|
Pre-made viral vector of LARS/LARS1 cDNA Clones/ORF Plasmid
LARS/LARS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51520 | Pre-made Human LARS1/LRS/LARS siRNA oligo Duplex | 51520 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo291624 | Pre-made Rat Lars1/Lars siRNA oligo Duplex | 291624 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107045 | Pre-made Mouse Lars1/Lars/leuRS siRNA oligo Duplex | 107045 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706792 | Pre-made Cynomolgus/Rhesus macaque LARS1/LARS siRNA oligo Duplex | 706792 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083060 | Pre-made Cat/Feline LARS1/LARS siRNA oligo Duplex | 101083060 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478051 | Pre-made Dog/Canine LARS1/LARS siRNA oligo Duplex | 478051 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509429 | Pre-made Bovines/Cattle LARS1/LARS siRNA oligo Duplex | 509429 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061092 | Pre-made Equine/Horse LARS1/LARS siRNA oligo Duplex | 100061092 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LARS/LARS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9459-Ab | Human | Anti-Human LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9459-Ab | Rat | Anti-Rat LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9459-Ab | Mouse | Anti-Mouse LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9459-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9459-Ab | Cat/Feline | Anti-Cat/Feline LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9459-Ab | Dog/Canine | Anti-Dog/Canine LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9459-Ab | Bovines/Cattle | Anti-Bovines/Cattle LARS/LARS1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9459-Ab | Equine/Horse | Anti-Equine/Horse LARS/LARS1 monoclonal antibody | mab | | Detail |
LARS/LARS1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9459-Ag | Human | Human LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9459-Ag | Rat | Rat LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9459-Ag | Mouse | Mouse LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9459-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9459-Ag | Cat/Feline | Cat/Feline LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9459-Ag | Dog/Canine | Dog/Canine LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9459-Ag | Bovines/Cattle | Bovines/Cattle LARS/LARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9459-Ag | Equine/Horse | Equine/Horse LARS/LARS1 recombinant protein | Mammalian cell | Detail |
