Explore POLK gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
| Target ID |
GM-IP9420
|
| Target Name |
POLK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
51426
|
| Gene ID |
100065534 (Equus caballus), 101099613 (Felis catus), 171525 (Rattus norvegicus), 27015 (Mus musculus)
479180 (Canis lupus familiaris), 51426 (Homo sapiens), 541218 (Bos taurus), 705713 (Macaca mulatta)
|
| Target Alternative Names |
DINB protein (DINP),DINB1,DINP,DNA polymerase kappa,Dinb1,POLK,POLQ,Polk
|
| Uniprot Accession |
Q9QUG2,Q9UBT6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000014876, ENSMUSG00000021668, ENSCAFG00845011326, ENSG00000122008, ENSBTAG00000004028, ENSMMUG00000006144
|
POLK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51426 | Pre-made Human POLK/DINP/POLQ siRNA oligo Duplex | 51426 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171525 | Pre-made Rat Polk/Dinb1 siRNA oligo Duplex | 171525 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo27015 | Pre-made Mouse Polk/DINP/Dinb1 siRNA oligo Duplex | 27015 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705713 | Pre-made Cynomolgus/Rhesus macaque POLK siRNA oligo Duplex | 705713 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099613 | Pre-made Cat/Feline POLK siRNA oligo Duplex | 101099613 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479180 | Pre-made Dog/Canine POLK siRNA oligo Duplex | 479180 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541218 | Pre-made Bovines/Cattle POLK siRNA oligo Duplex | 541218 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065534 | Pre-made Equine/Horse POLK siRNA oligo Duplex | 100065534 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
POLK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9420-Ab | Human | Anti-Human POLK monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9420-Ab | Rat | Anti-Rat POLK monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9420-Ab | Mouse | Anti-Mouse POLK monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9420-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque POLK monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9420-Ab | Cat/Feline | Anti-Cat/Feline POLK monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9420-Ab | Dog/Canine | Anti-Dog/Canine POLK monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9420-Ab | Bovines/Cattle | Anti-Bovines/Cattle POLK monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9420-Ab | Equine/Horse | Anti-Equine/Horse POLK monoclonal antibody | mab | | Detail |
POLK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9420-Ag | Human | Human POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9420-Ag | Rat | Rat POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9420-Ag | Mouse | Mouse POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9420-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9420-Ag | Cat/Feline | Cat/Feline POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9420-Ag | Dog/Canine | Dog/Canine POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9420-Ag | Bovines/Cattle | Bovines/Cattle POLK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9420-Ag | Equine/Horse | Equine/Horse POLK recombinant protein | Mammalian cell | Detail |
