Explore Neurofibromin 1/Neurofibromin/NF1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP9088
|
| Target Name |
Neurofibromin 1/Neurofibromin/NF1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4763
|
| Gene ID |
100071896 (Equus caballus), 101092407 (Felis catus), 18015 (Mus musculus), 24592 (Rattus norvegicus)
280877 (Bos taurus), 4763 (Homo sapiens), 480618 (Canis lupus familiaris), 712911 (Macaca mulatta)
|
| Target Alternative Names |
Dsk9,E030030H24Rik,Mhdadsk9,NF1,NFNS,Neurofibromatosis-related protein NF-1,Neurofibromin,Neurofibromin 1,Nf-1,Nf1,VRNF,WSS
|
| Uniprot Accession |
Q04690,P97526,P21359
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer, malignant peripheral nerve sheath tumors, myeloid leukemias, Neuromas, juvenile pilocytic astrocytomas
|
| Gene Ensembl |
ENSECAG00000008317, ENSMUSG00000020716, ENSBTAG00000050242, ENSG00000196712, ENSCAFG00845014199, ENSMMUG00000008605
|
Neurofibromin 1/Neurofibromin/NF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4763 | Pre-made Human NF1/WSS/NFNS siRNA oligo Duplex | 4763 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24592 | Pre-made Rat Nf1 siRNA oligo Duplex | 24592 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18015 | Pre-made Mouse Nf1/Dsk9/Nf-1 siRNA oligo Duplex | 18015 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712911 | Pre-made Cynomolgus/Rhesus macaque NF1 siRNA oligo Duplex | 712911 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092407 | Pre-made Cat/Feline NF1 siRNA oligo Duplex | 101092407 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480618 | Pre-made Dog/Canine NF1 siRNA oligo Duplex | 480618 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280877 | Pre-made Bovines/Cattle NF1 siRNA oligo Duplex | 280877 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071896 | Pre-made Equine/Horse NF1 siRNA oligo Duplex | 100071896 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Neurofibromin 1/Neurofibromin/NF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9088-Ab | Human | Anti-Human Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9088-Ab | Rat | Anti-Rat Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9088-Ab | Mouse | Anti-Mouse Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9088-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9088-Ab | Cat/Feline | Anti-Cat/Feline Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9088-Ab | Dog/Canine | Anti-Dog/Canine Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9088-Ab | Bovines/Cattle | Anti-Bovines/Cattle Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9088-Ab | Equine/Horse | Anti-Equine/Horse Neurofibromin 1/Neurofibromin/NF1 monoclonal antibody | mab | | Detail |
Neurofibromin 1/Neurofibromin/NF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9088-Ag | Human | Human Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9088-Ag | Rat | Rat Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9088-Ag | Mouse | Mouse Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9088-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9088-Ag | Cat/Feline | Cat/Feline Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9088-Ag | Dog/Canine | Dog/Canine Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9088-Ag | Bovines/Cattle | Bovines/Cattle Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9088-Ag | Equine/Horse | Equine/Horse Neurofibromin 1/Neurofibromin/NF1 recombinant protein | Mammalian cell | Detail |
