Explore c-MAF/MAF gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
| Target ID |
GM-IP8779
|
| Target Name |
c-MAF/MAF
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4094
|
| Gene ID |
100146831 (Equus caballus), 102156419 (Canis lupus familiaris), 102900229 (Felis catus), 106995090 (Macaca mulatta) 17132 (Mus musculus), 4094 (Homo sapiens), 54267 (Rattus norvegicus), 782481 (Bos taurus)
|
| Target Alternative Names |
2810401A20Rik,A230108G15Rik,AYGRP,C-Maf,CCA4,CTRCT21,MAF,Maf,Maf2,Proto-oncogene c-Maf,Transcription factor Maf,V-maf musculoaponeurotic fibrosarcoma oncogene homolog,c-MAF,c-maf,cMaf
|
| Uniprot Accession |
P54843,O75444,P54844,A7Z017
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSMMUG00000037756, ENSMUSG00000055435, ENSG00000178573, ENSBTAG00000044192
|
Pre-made viral vector of c-MAF/MAF cDNA Clones/ORF Plasmid
c-MAF/MAF siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4094 | Pre-made Human MAF/CCA4/AYGRP siRNA oligo Duplex | 4094 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54267 | Pre-made Rat Maf/Maf2/cMaf siRNA oligo Duplex | 54267 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17132 | Pre-made Mouse Maf/c-maf/2810401A20Rik siRNA oligo Duplex | 17132 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106995090 | Pre-made Cynomolgus/Rhesus macaque MAF siRNA oligo Duplex | 106995090 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102900229 | Pre-made Cat/Feline MAF siRNA oligo Duplex | 102900229 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102156419 | Pre-made Dog/Canine MAF siRNA oligo Duplex | 102156419 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo782481 | Pre-made Bovines/Cattle MAF/C-Maf siRNA oligo Duplex | 782481 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146831 | Pre-made Equine/Horse MAF siRNA oligo Duplex | 100146831 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
c-MAF/MAF antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8779-Ab | Human | Anti-Human c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8779-Ab | Rat | Anti-Rat c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8779-Ab | Mouse | Anti-Mouse c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8779-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8779-Ab | Cat/Feline | Anti-Cat/Feline c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8779-Ab | Dog/Canine | Anti-Dog/Canine c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8779-Ab | Bovines/Cattle | Anti-Bovines/Cattle c-MAF/MAF monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8779-Ab | Equine/Horse | Anti-Equine/Horse c-MAF/MAF monoclonal antibody | mab | | Detail |
c-MAF/MAF recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8779-Ag | Human | Human c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8779-Ag | Rat | Rat c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8779-Ag | Mouse | Mouse c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8779-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8779-Ag | Cat/Feline | Cat/Feline c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8779-Ag | Dog/Canine | Dog/Canine c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8779-Ag | Bovines/Cattle | Bovines/Cattle c-MAF/MAF recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8779-Ag | Equine/Horse | Equine/Horse c-MAF/MAF recombinant protein | Mammalian cell | Detail |