Explore MXD1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
| Target ID |
GM-IP8774
|
| Target Name |
MXD1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4084
|
| Gene ID |
100060923 (Equus caballus), 101095166 (Felis catus), 17119 (Mus musculus), 362391 (Rattus norvegicus)
4084 (Homo sapiens), 514626 (Bos taurus), 612631 (Canis lupus familiaris), 701784 (Macaca mulatta)
|
| Target Alternative Names |
BHLHC58,MAD,MAD1,MXD1,Mad,Mad-1,Mad1,Max dimerization protein 1,Max dimerizer 1,Mxd1,Protein MAD
|
| Uniprot Accession |
P50538,Q05195
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSMUSG00000001156, ENSG00000059728, ENSBTAG00000001042, ENSCAFG00845027010, ENSMMUG00000010226
|
Pre-made viral vector of MXD1 cDNA Clones/ORF Plasmid
MXD1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4084 | Pre-made Human MXD1/MAD/MAD1 siRNA oligo Duplex | 4084 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362391 | Pre-made Rat Mxd1/Mad-1 siRNA oligo Duplex | 362391 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17119 | Pre-made Mouse Mxd1/Mad/Mad1 siRNA oligo Duplex | 17119 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701784 | Pre-made Cynomolgus/Rhesus macaque MXD1 siRNA oligo Duplex | 701784 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095166 | Pre-made Cat/Feline MXD1 siRNA oligo Duplex | 101095166 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612631 | Pre-made Dog/Canine MXD1/MAD1 siRNA oligo Duplex | 612631 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514626 | Pre-made Bovines/Cattle MXD1 siRNA oligo Duplex | 514626 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060923 | Pre-made Equine/Horse MXD1 siRNA oligo Duplex | 100060923 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MXD1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8774-Ab | Human | Anti-Human MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8774-Ab | Rat | Anti-Rat MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8774-Ab | Mouse | Anti-Mouse MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8774-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8774-Ab | Cat/Feline | Anti-Cat/Feline MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8774-Ab | Dog/Canine | Anti-Dog/Canine MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8774-Ab | Bovines/Cattle | Anti-Bovines/Cattle MXD1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8774-Ab | Equine/Horse | Anti-Equine/Horse MXD1 monoclonal antibody | mab | | Detail |
MXD1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8774-Ag | Human | Human MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8774-Ag | Rat | Rat MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8774-Ag | Mouse | Mouse MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8774-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8774-Ag | Cat/Feline | Cat/Feline MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8774-Ag | Dog/Canine | Dog/Canine MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8774-Ag | Bovines/Cattle | Bovines/Cattle MXD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8774-Ag | Equine/Horse | Equine/Horse MXD1 recombinant protein | Mammalian cell | Detail |
