Explore Cytokeratin 18/KRT18 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP8462
|
| Target Name |
Cytokeratin 18/KRT18
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3875
|
| Gene ID |
100063542 (Equus caballus), 100169946 (Felis catus), 16668 (Mus musculus), 294853 (Rattus norvegicus) 3875 (Homo sapiens), 477601 (Canis lupus familiaris), 506480 (Bos taurus), 700569 (Macaca mulatta)
|
| Target Alternative Names |
CK-18,CK18,CYK18,Cell proliferation-inducing gene 46 protein,Cytokeratin 18,Cytokeratin-18 (CK-18),K18,KRT18,Keratin,Keratin-18 (K18),Krt1-18,Krt18,type I cytoskeletal 18
|
| Uniprot Accession |
P05784,Q5BJY9,P05783
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer, breast lesions
|
| Gene Ensembl |
ENSECAG00000038379, ENSMUSG00000023043, ENSG00000111057, ENSCAFG00845023645, ENSBTAG00000001517, ENSMMUG00000031911
|
Pre-made viral vector of Cytokeratin 18/KRT18 cDNA Clones/ORF Plasmid
Cytokeratin 18/KRT18 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3875 | Pre-made Human KRT18/K18/CK-18 siRNA oligo Duplex | 3875 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294853 | Pre-made Rat Krt18/Krt1-18 siRNA oligo Duplex | 294853 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16668 | Pre-made Mouse Krt18/K18/CK18 siRNA oligo Duplex | 16668 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700569 | Pre-made Cynomolgus/Rhesus macaque KRT18 siRNA oligo Duplex | 700569 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100169946 | Pre-made Cat/Feline KRT18 siRNA oligo Duplex | 100169946 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477601 | Pre-made Dog/Canine KRT18/CK18 siRNA oligo Duplex | 477601 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506480 | Pre-made Bovines/Cattle KRT18 siRNA oligo Duplex | 506480 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063542 | Pre-made Equine/Horse KRT18 siRNA oligo Duplex | 100063542 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cytokeratin 18/KRT18 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8462-Ab | Human | Anti-Human Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8462-Ab | Rat | Anti-Rat Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8462-Ab | Mouse | Anti-Mouse Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8462-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8462-Ab | Cat/Feline | Anti-Cat/Feline Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8462-Ab | Dog/Canine | Anti-Dog/Canine Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8462-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8462-Ab | Equine/Horse | Anti-Equine/Horse Cytokeratin 18/KRT18 monoclonal antibody | mab | | Detail |
Cytokeratin 18/KRT18 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8462-Ag | Human | Human Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8462-Ag | Rat | Rat Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8462-Ag | Mouse | Mouse Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8462-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8462-Ag | Cat/Feline | Cat/Feline Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8462-Ag | Dog/Canine | Dog/Canine Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8462-Ag | Bovines/Cattle | Bovines/Cattle Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8462-Ag | Equine/Horse | Equine/Horse Cytokeratin 18/KRT18 recombinant protein | Mammalian cell | Detail |