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Target
sublocation: Introcelluar Protein.
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP8267
|
| Target Name |
APRT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
353
|
| Gene ID |
100051212 (Equus caballus), 101098913 (Felis catus), 11821 (Mus musculus), 292072 (Rattus norvegicus)
353 (Homo sapiens), 479615 (Canis lupus familiaris), 519017 (Bos taurus), 697715 (Macaca mulatta)
|
| Target Alternative Names |
AMP,APRT,APRTD,Adenine phosphoribosyltransferase,Aprt
|
| Uniprot Accession |
P08030,P36972,P07741,Q56JW4
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSMUSG00000006589, ENSG00000198931, ENSCAFG00845003116, ENSMMUG00000012430
|
Pre-made viral vector of APRT cDNA Clones/ORF Plasmid
APRT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo353 | Pre-made Human APRT/AMP/APRTD siRNA oligo Duplex | 353 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292072 | Pre-made Rat Aprt siRNA oligo Duplex | 292072 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11821 | Pre-made Mouse Aprt siRNA oligo Duplex | 11821 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697715 | Pre-made Cynomolgus/Rhesus macaque APRT siRNA oligo Duplex | 697715 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098913 | Pre-made Cat/Feline APRT siRNA oligo Duplex | 101098913 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479615 | Pre-made Dog/Canine APRT siRNA oligo Duplex | 479615 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519017 | Pre-made Bovines/Cattle APRT siRNA oligo Duplex | 519017 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051212 | Pre-made Equine/Horse APRT siRNA oligo Duplex | 100051212 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
APRT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8267-Ab | Human | Anti-Human APRT monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8267-Ab | Rat | Anti-Rat APRT monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8267-Ab | Mouse | Anti-Mouse APRT monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8267-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque APRT monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8267-Ab | Cat/Feline | Anti-Cat/Feline APRT monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8267-Ab | Dog/Canine | Anti-Dog/Canine APRT monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8267-Ab | Bovines/Cattle | Anti-Bovines/Cattle APRT monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8267-Ab | Equine/Horse | Anti-Equine/Horse APRT monoclonal antibody | mab | | Detail |
APRT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8267-Ag | Human | Human APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8267-Ag | Rat | Rat APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8267-Ag | Mouse | Mouse APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8267-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8267-Ag | Cat/Feline | Cat/Feline APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8267-Ag | Dog/Canine | Dog/Canine APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8267-Ag | Bovines/Cattle | Bovines/Cattle APRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8267-Ag | Equine/Horse | Equine/Horse APRT recombinant protein | Mammalian cell | Detail |
