Explore POT1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP7179
|
| Target Name |
POT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
25913
|
| Gene ID |
100071610 (Equus caballus), 101097225 (Felis catus), 101185 (Mus musculus), 25913 (Homo sapiens)
500054 (Rattus norvegicus), 511292 (Bos taurus), 609119 (Canis lupus familiaris), 696751 (Macaca mulatta)
|
| Target Alternative Names |
1500031H18Rik,CMM10,CRMCC3,GLM9,HPOT1,PFBMFT8,POT1,POT1-like telomere end-binding protein,Pot1,Pot1a,Protection of telomeres protein 1,TPDS3,hPot1
|
| Uniprot Accession |
Q91WC1,Q9NUX5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000008647, ENSMUSG00000029676, ENSG00000128513, ENSBTAG00000013180, ENSCAFG00845005675, ENSMMUG00000020587
|
POT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo25913 | Pre-made Human POT1/GLM9/CMM10 siRNA oligo Duplex | 25913 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500054 | Pre-made Rat Pot1/Pot1a siRNA oligo Duplex | 500054 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101185 | Pre-made Mouse Pot1a/Pot1/1500031H18Rik siRNA oligo Duplex | 101185 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696751 | Pre-made Cynomolgus/Rhesus macaque POT1 siRNA oligo Duplex | 696751 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097225 | Pre-made Cat/Feline POT1 siRNA oligo Duplex | 101097225 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609119 | Pre-made Dog/Canine POT1 siRNA oligo Duplex | 609119 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511292 | Pre-made Bovines/Cattle POT1 siRNA oligo Duplex | 511292 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071610 | Pre-made Equine/Horse POT1 siRNA oligo Duplex | 100071610 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
POT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7179-Ab | Human | Anti-Human POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7179-Ab | Rat | Anti-Rat POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7179-Ab | Mouse | Anti-Mouse POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7179-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7179-Ab | Cat/Feline | Anti-Cat/Feline POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7179-Ab | Dog/Canine | Anti-Dog/Canine POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7179-Ab | Bovines/Cattle | Anti-Bovines/Cattle POT1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7179-Ab | Equine/Horse | Anti-Equine/Horse POT1 monoclonal antibody | mab | | Detail |
POT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7179-Ag | Human | Human POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7179-Ag | Rat | Rat POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7179-Ag | Mouse | Mouse POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7179-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7179-Ag | Cat/Feline | Cat/Feline POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7179-Ag | Dog/Canine | Dog/Canine POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7179-Ag | Bovines/Cattle | Bovines/Cattle POT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7179-Ag | Equine/Horse | Equine/Horse POT1 recombinant protein | Mammalian cell | Detail |
