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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Target ID |
GM-IP7134
|
Target Name |
GAK
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2580
|
Gene ID |
100051853 (Equus caballus), 101094018 (Felis catus), 231580 (Mus musculus), 2580 (Homo sapiens) 479133 (Canis lupus familiaris), 511296 (Bos taurus), 703406 (Macaca mulatta), 81659 (Rattus norvegicus)
|
Target Alternative Names |
Cyclin-G-associated kinase,D130045N16Rik,DNAJ26,DNAJC26,DnaJ homolog subfamily C member 26,GAK,Gak
|
Uniprot Accession |
Q99KY4,O14976,P97874
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Life Science Target
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000023832, ENSMUSG00000062234, ENSG00000178950, ENSCAFG00845001290, ENSBTAG00000019188, ENSMMUG00000016919
|
Target Classification |
Kinase
|
GAK siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo2580 | Pre-made Human GAK/DNAJ26/DNAJC26 siRNA oligo Duplex | 2580 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo81659 | Pre-made Rat Gak siRNA oligo Duplex | 81659 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo231580 | Pre-made Mouse Gak/D130045N16Rik siRNA oligo Duplex | 231580 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo703406 | Pre-made Cynomolgus/Rhesus macaque GAK siRNA oligo Duplex | 703406 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101094018 | Pre-made Cat/Feline GAK siRNA oligo Duplex | 101094018 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo479133 | Pre-made Dog/Canine GAK siRNA oligo Duplex | 479133 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo511296 | Pre-made Bovines/Cattle GAK siRNA oligo Duplex | 511296 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100051853 | Pre-made Equine/Horse GAK siRNA oligo Duplex | 100051853 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GAK antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-IP7134-Ab | Human | Anti-Human GAK monoclonal antibody | mab | | Detail |
GM-Tg-rg-IP7134-Ab | Rat | Anti-Rat GAK monoclonal antibody | mab | | Detail |
GM-Tg-mg-IP7134-Ab | Mouse | Anti-Mouse GAK monoclonal antibody | mab | | Detail |
GM-Tg-cynog-IP7134-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GAK monoclonal antibody | mab | | Detail |
GM-Tg-felg-IP7134-Ab | Cat/Feline | Anti-Cat/Feline GAK monoclonal antibody | mab | | Detail |
GM-Tg-cang-IP7134-Ab | Dog/Canine | Anti-Dog/Canine GAK monoclonal antibody | mab | | Detail |
GM-Tg-bovg-IP7134-Ab | Bovines/Cattle | Anti-Bovines/Cattle GAK monoclonal antibody | mab | | Detail |
GM-Tg-equg-IP7134-Ab | Equine/Horse | Anti-Equine/Horse GAK monoclonal antibody | mab | | Detail |
GAK recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-IP7134-Ag | Human | Human GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-IP7134-Ag | Rat | Rat GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-IP7134-Ag | Mouse | Mouse GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-IP7134-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-IP7134-Ag | Cat/Feline | Cat/Feline GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-IP7134-Ag | Dog/Canine | Dog/Canine GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-IP7134-Ag | Bovines/Cattle | Bovines/Cattle GAK recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-IP7134-Ag | Equine/Horse | Equine/Horse GAK recombinant protein | Mammalian cell | Detail |