Explore IQSEC2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
| Target ID |
GM-IP6723
|
| Target Name |
IQSEC2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
23096
|
| Gene ID |
101091849 (Felis catus), 106781352 (Equus caballus), 23096 (Homo sapiens), 245666 (Mus musculus) 491895 (Canis lupus familiaris), 517311 (Bos taurus), 685244 (Rattus norvegicus), 702562 (Macaca mulatta)
|
| Target Alternative Names |
BRAG1,Brag1,IQ motif and SEC7 domain-containing protein 2,IQ-ArfGEF,IQSEC2,Iqsec2,MRX1,MRX18,MRX78,RGD1562109,XLID1
|
| Uniprot Accession |
Q5JU85,Q5DU25
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000021698, ENSG00000124313, ENSMUSG00000041115, ENSCAFG00845028820, ENSBTAG00000014945, ENSMMUG00000020555
|
IQSEC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23096 | Pre-made Human IQSEC2/MRX1/BRAG1 siRNA oligo Duplex | 23096 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo685244 | Pre-made Rat Iqsec2/RGD1562109 siRNA oligo Duplex | 685244 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo245666 | Pre-made Mouse Iqsec2/Brag1 siRNA oligo Duplex | 245666 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702562 | Pre-made Cynomolgus/Rhesus macaque IQSEC2 siRNA oligo Duplex | 702562 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091849 | Pre-made Cat/Feline IQSEC2 siRNA oligo Duplex | 101091849 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491895 | Pre-made Dog/Canine IQSEC2 siRNA oligo Duplex | 491895 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517311 | Pre-made Bovines/Cattle IQSEC2 siRNA oligo Duplex | 517311 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106781352 | Pre-made Equine/Horse IQSEC2 siRNA oligo Duplex | 106781352 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IQSEC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6723-Ab | Human | Anti-Human IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6723-Ab | Rat | Anti-Rat IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6723-Ab | Mouse | Anti-Mouse IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6723-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6723-Ab | Cat/Feline | Anti-Cat/Feline IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6723-Ab | Dog/Canine | Anti-Dog/Canine IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6723-Ab | Bovines/Cattle | Anti-Bovines/Cattle IQSEC2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6723-Ab | Equine/Horse | Anti-Equine/Horse IQSEC2 monoclonal antibody | mab | | Detail |
IQSEC2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6723-Ag | Human | Human IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6723-Ag | Rat | Rat IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6723-Ag | Mouse | Mouse IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6723-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6723-Ag | Cat/Feline | Cat/Feline IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6723-Ag | Dog/Canine | Dog/Canine IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6723-Ag | Bovines/Cattle | Bovines/Cattle IQSEC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6723-Ag | Equine/Horse | Equine/Horse IQSEC2 recombinant protein | Mammalian cell | Detail |