Explore SETX gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP6706
|
| Target Name |
SETX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23064
|
| Gene ID |
100066679 (Equus caballus), 101100009 (Felis catus), 23064 (Homo sapiens), 269254 (Mus musculus)
362096 (Rattus norvegicus), 480691 (Canis lupus familiaris), 534284 (Bos taurus), 715065 (Macaca mulatta)
|
| Target Alternative Names |
A130090N03,A930037J23Rik,ALS4,AOA2,Als4,Amyotrophic lateral sclerosis 4 protein,Probable helicase senataxin,RGD1565575,SCAN2,SCAR1,SEN1 homolog,SETX,STEX,Sen1,Senataxin,Setx,bA479K20.2,mKIAA0625
|
| Uniprot Accession |
Q7Z333,A2AKX3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000012019, ENSG00000107290, ENSMUSG00000043535, ENSCAFG00845017137, ENSBTAG00000024822, ENSMMUG00000018468
|
SETX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23064 | Pre-made Human SETX/ALS4/AOA2 siRNA oligo Duplex | 23064 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362096 | Pre-made Rat Setx/RGD1565575 siRNA oligo Duplex | 362096 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo269254 | Pre-made Mouse Setx/AOA2/Als4 siRNA oligo Duplex | 269254 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715065 | Pre-made Cynomolgus/Rhesus macaque SETX siRNA oligo Duplex | 715065 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100009 | Pre-made Cat/Feline SETX siRNA oligo Duplex | 101100009 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480691 | Pre-made Dog/Canine SETX siRNA oligo Duplex | 480691 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534284 | Pre-made Bovines/Cattle SETX siRNA oligo Duplex | 534284 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066679 | Pre-made Equine/Horse SETX siRNA oligo Duplex | 100066679 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SETX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6706-Ab | Human | Anti-Human SETX monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6706-Ab | Rat | Anti-Rat SETX monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6706-Ab | Mouse | Anti-Mouse SETX monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6706-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SETX monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6706-Ab | Cat/Feline | Anti-Cat/Feline SETX monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6706-Ab | Dog/Canine | Anti-Dog/Canine SETX monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6706-Ab | Bovines/Cattle | Anti-Bovines/Cattle SETX monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6706-Ab | Equine/Horse | Anti-Equine/Horse SETX monoclonal antibody | mab | | Detail |
SETX recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6706-Ag | Human | Human SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6706-Ag | Rat | Rat SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6706-Ag | Mouse | Mouse SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6706-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6706-Ag | Cat/Feline | Cat/Feline SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6706-Ag | Dog/Canine | Dog/Canine SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6706-Ag | Bovines/Cattle | Bovines/Cattle SETX recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6706-Ag | Equine/Horse | Equine/Horse SETX recombinant protein | Mammalian cell | Detail |
