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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
| Target ID |
GM-IP6601
|
| Target Name |
ADGRL1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
22859
|
| Gene ID |
100065569 (Equus caballus), 101091175 (Felis catus), 22859 (Homo sapiens), 330814 (Mus musculus) 610349 (Canis lupus familiaris), 65096 (Rattus norvegicus), 718708 (Macaca mulatta), 788252 (Bos taurus)
|
| Target Alternative Names |
2900070I05Rik,ADGRL1,Adgrl1,Adhesion G protein-coupled receptor L1,CIRL1,CL1,CL1BA,CLIBA,Calcium-independent alpha-latrotoxin receptor 1 (CIRL-1),DEDBANP,LEC2,LPHN1,Latrophilin-1,Lec2,Lectomedin-2,Lphn1,mKIAA0821
|
| Uniprot Accession |
O94910,Q80TR1,O88917,O97831
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000021555, ENSG00000072071, ENSMUSG00000013033, ENSCAFG00845023599, ENSMMUG00000014137, ENSBTAG00000003675
|
ADGRL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo22859 | Pre-made Human ADGRL1/CL1/LEC2 siRNA oligo Duplex | 22859 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65096 | Pre-made Rat Adgrl1/CL1BA/Lphn1 siRNA oligo Duplex | 65096 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo330814 | Pre-made Mouse Adgrl1/Lec2/CLIBA siRNA oligo Duplex | 330814 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718708 | Pre-made Cynomolgus/Rhesus macaque ADGRL1/LPHN1 siRNA oligo Duplex | 718708 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091175 | Pre-made Cat/Feline ADGRL1 siRNA oligo Duplex | 101091175 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610349 | Pre-made Dog/Canine ADGRL1/LPHN1 siRNA oligo Duplex | 610349 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo788252 | Pre-made Bovines/Cattle ADGRL1/LPHN1 siRNA oligo Duplex | 788252 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065569 | Pre-made Equine/Horse ADGRL1/LPHN1 siRNA oligo Duplex | 100065569 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADGRL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6601-Ab | Human | Anti-Human ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6601-Ab | Rat | Anti-Rat ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6601-Ab | Mouse | Anti-Mouse ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6601-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6601-Ab | Cat/Feline | Anti-Cat/Feline ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6601-Ab | Dog/Canine | Anti-Dog/Canine ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6601-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADGRL1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6601-Ab | Equine/Horse | Anti-Equine/Horse ADGRL1 monoclonal antibody | mab | | Detail |
ADGRL1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6601-Ag | Human | Human ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6601-Ag | Rat | Rat ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6601-Ag | Mouse | Mouse ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6601-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6601-Ag | Cat/Feline | Cat/Feline ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6601-Ag | Dog/Canine | Dog/Canine ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6601-Ag | Bovines/Cattle | Bovines/Cattle ADGRL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6601-Ag | Equine/Horse | Equine/Horse ADGRL1 recombinant protein | Mammalian cell | Detail |