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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP6433
|
| Target Name |
FBL
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2091
|
| Gene ID |
100064571 (Equus caballus), 101094807 (Felis catus), 14113 (Mus musculus), 2091 (Homo sapiens)
292747 (Rattus norvegicus), 476460 (Canis lupus familiaris), 538548 (Bos taurus), 700286 (Macaca mulatta)
|
| Target Alternative Names |
34 kDa nucleolar scleroderma antigen,FBL,FIB,FLRN,Fbl,Histone-glutamine methyltransferase,Nop1,RNU3IP1,U6 snRNA 2'-O-methyltransferase fibrillarin,rRNA 2'-O-methyltransferase fibrillarin
|
| Uniprot Accession |
P35550,P22087,P22509
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000023221, ENSMUSG00000046865, ENSG00000105202, ENSCAFG00845004182, ENSBTAG00000002579, ENSMMUG00000022725
|
Pre-made viral vector of FBL cDNA Clones/ORF Plasmid
FBL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2091 | Pre-made Human FBL/FIB/FLRN siRNA oligo Duplex | 2091 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292747 | Pre-made Rat Fbl siRNA oligo Duplex | 292747 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14113 | Pre-made Mouse Fbl/FIB/FLRN siRNA oligo Duplex | 14113 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700286 | Pre-made Cynomolgus/Rhesus macaque FBL siRNA oligo Duplex | 700286 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094807 | Pre-made Cat/Feline FBL siRNA oligo Duplex | 101094807 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476460 | Pre-made Dog/Canine FBL siRNA oligo Duplex | 476460 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538548 | Pre-made Bovines/Cattle FBL siRNA oligo Duplex | 538548 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064571 | Pre-made Equine/Horse FBL siRNA oligo Duplex | 100064571 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FBL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6433-Ab | Human | Anti-Human FBL monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6433-Ab | Rat | Anti-Rat FBL monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6433-Ab | Mouse | Anti-Mouse FBL monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6433-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FBL monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6433-Ab | Cat/Feline | Anti-Cat/Feline FBL monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6433-Ab | Dog/Canine | Anti-Dog/Canine FBL monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6433-Ab | Bovines/Cattle | Anti-Bovines/Cattle FBL monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6433-Ab | Equine/Horse | Anti-Equine/Horse FBL monoclonal antibody | mab | | Detail |
FBL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6433-Ag | Human | Human FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6433-Ag | Rat | Rat FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6433-Ag | Mouse | Mouse FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6433-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6433-Ag | Cat/Feline | Cat/Feline FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6433-Ag | Dog/Canine | Dog/Canine FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6433-Ag | Bovines/Cattle | Bovines/Cattle FBL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6433-Ag | Equine/Horse | Equine/Horse FBL recombinant protein | Mammalian cell | Detail |
