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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP6365
|
| Target Name |
EML1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2009
|
| Gene ID |
100050910 (Equus caballus), 101091632 (Felis catus), 2009 (Homo sapiens), 362783 (Rattus norvegicus) 490853 (Canis lupus familiaris), 512904 (Bos taurus), 68519 (Mus musculus), 705977 (Macaca mulatta)
|
| Target Alternative Names |
1110008N23Rik,A930030P13Rik,BH,ELP79,EMAP,EMAP-1,EMAPL,EML1,Echinoderm microtubule-associated protein-like 1,Eml1,HuEMAP-1,heco
|
| Uniprot Accession |
O00423,Q4V8C3,Q05BC3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000019766, ENSG00000066629, ENSCAFG00845004114, ENSBTAG00000013491, ENSMUSG00000058070, ENSMMUG00000011706
|
EML1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2009 | Pre-made Human EML1/BH/EMAP siRNA oligo Duplex | 2009 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362783 | Pre-made Rat Eml1 siRNA oligo Duplex | 362783 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo68519 | Pre-made Mouse Eml1/EMAP/heco siRNA oligo Duplex | 68519 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705977 | Pre-made Cynomolgus/Rhesus macaque EML1 siRNA oligo Duplex | 705977 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091632 | Pre-made Cat/Feline EML1 siRNA oligo Duplex | 101091632 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490853 | Pre-made Dog/Canine EML1 siRNA oligo Duplex | 490853 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512904 | Pre-made Bovines/Cattle EML1/EMAPL siRNA oligo Duplex | 512904 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050910 | Pre-made Equine/Horse EML1 siRNA oligo Duplex | 100050910 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EML1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6365-Ab | Human | Anti-Human EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6365-Ab | Rat | Anti-Rat EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6365-Ab | Mouse | Anti-Mouse EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6365-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6365-Ab | Cat/Feline | Anti-Cat/Feline EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6365-Ab | Dog/Canine | Anti-Dog/Canine EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6365-Ab | Bovines/Cattle | Anti-Bovines/Cattle EML1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6365-Ab | Equine/Horse | Anti-Equine/Horse EML1 monoclonal antibody | mab | | Detail |
EML1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6365-Ag | Human | Human EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6365-Ag | Rat | Rat EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6365-Ag | Mouse | Mouse EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6365-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6365-Ag | Cat/Feline | Cat/Feline EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6365-Ag | Dog/Canine | Dog/Canine EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6365-Ag | Bovines/Cattle | Bovines/Cattle EML1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6365-Ag | Equine/Horse | Equine/Horse EML1 recombinant protein | Mammalian cell | Detail |