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Target
sublocation: Introcelluar Protein.
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
| Target ID |
GM-IP6350
|
| Target Name |
APOBEC3A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
200315
|
| Gene ID |
200315 (Homo sapiens), 721030 (Macaca mulatta)
|
| Target Alternative Names |
A3A,APOBEC3A,ARP3,DNA dC->dU-editing enzyme APOBEC-3A,PHRBN,Phorbolin-1,bK150C2.1
|
| Uniprot Accession |
P31941
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSG00000128383, ENSMMUG00000042504
|
APOBEC3A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo200315 | Pre-made Human APOBEC3A/A3A/ARP3 siRNA oligo Duplex | 200315 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721030 | Pre-made Cynomolgus/Rhesus macaque APOBEC3A siRNA oligo Duplex | 721030 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
APOBEC3A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6350-Ab | Human | Anti-Human APOBEC3A monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6350-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque APOBEC3A monoclonal antibody | mab | | Detail |
APOBEC3A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6350-Ag | Human | Human APOBEC3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6350-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque APOBEC3A recombinant protein | Mammalian cell | Detail |
