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Target
sublocation: Introcelluar Protein.
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
| Target ID |
GM-IP6296
|
| Target Name |
EIF2S1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1965
|
| Gene ID |
100052709 (Equus caballus), 101091455 (Felis catus), 13665 (Mus musculus), 1965 (Homo sapiens) 327694 (Bos taurus), 480361 (Canis lupus familiaris), 54318 (Rattus norvegicus), 710150 (Macaca mulatta)
|
| Target Alternative Names |
0910001O23Rik,2410026C18Rik,35kDa,EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A,EIF2S1,Eif2a,Eif2s1,Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha,eIF-2A,eIF-2alpha,eIF2-alpha),eIF2alpha
|
| Uniprot Accession |
Q6ZWX6,P05198,P68102,P68101
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000018424, ENSMUSG00000021116, ENSG00000134001, ENSBTAG00000016311, ENSCAFG00845003308, ENSMMUG00000021419
|
Pre-made viral vector of EIF2S1 cDNA Clones/ORF Plasmid
EIF2S1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1965 | Pre-made Human EIF2S1/EIF2/EIF-2 siRNA oligo Duplex | 1965 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54318 | Pre-made Rat Eif2s1 siRNA oligo Duplex | 54318 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13665 | Pre-made Mouse Eif2s1/35kDa/Eif2a siRNA oligo Duplex | 13665 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710150 | Pre-made Cynomolgus/Rhesus macaque EIF2S1 siRNA oligo Duplex | 710150 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091455 | Pre-made Cat/Feline EIF2S1 siRNA oligo Duplex | 101091455 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480361 | Pre-made Dog/Canine EIF2S1 siRNA oligo Duplex | 480361 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo327694 | Pre-made Bovines/Cattle EIF2S1 siRNA oligo Duplex | 327694 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052709 | Pre-made Equine/Horse EIF2S1 siRNA oligo Duplex | 100052709 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EIF2S1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6296-Ab | Human | Anti-Human EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6296-Ab | Rat | Anti-Rat EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6296-Ab | Mouse | Anti-Mouse EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6296-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6296-Ab | Cat/Feline | Anti-Cat/Feline EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6296-Ab | Dog/Canine | Anti-Dog/Canine EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6296-Ab | Bovines/Cattle | Anti-Bovines/Cattle EIF2S1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6296-Ab | Equine/Horse | Anti-Equine/Horse EIF2S1 monoclonal antibody | mab | | Detail |
EIF2S1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6296-Ag | Human | Human EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6296-Ag | Rat | Rat EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6296-Ag | Mouse | Mouse EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6296-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6296-Ag | Cat/Feline | Cat/Feline EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6296-Ag | Dog/Canine | Dog/Canine EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6296-Ag | Bovines/Cattle | Bovines/Cattle EIF2S1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6296-Ag | Equine/Horse | Equine/Horse EIF2S1 recombinant protein | Mammalian cell | Detail |