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Target
sublocation: Introcelluar Protein.
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
| Target ID |
GM-IP6230
|
| Target Name |
DNM2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1785
|
| Gene ID |
100057627 (Equus caballus), 101100788 (Felis catus), 13430 (Mus musculus), 1785 (Homo sapiens) 25751 (Rattus norvegicus), 484949 (Canis lupus familiaris), 511691 (Bos taurus), 713558 (Macaca mulatta)
|
| Target Alternative Names |
CMT2M,CMTDI1,CMTDIB,DI-CMTB,DNM2,DYIIAAB,DYN2,DYNII,Dnm2,Dyn2,Dynamin 2,Dynamin II,Dynamin-2,LCCS5,Udnm,b2b2159Clo
|
| Uniprot Accession |
P39054,P50570,P39052,A6H7I5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000022341, ENSMUSG00000033335, ENSG00000079805, ENSCAFG00845023306, ENSBTAG00000013362, ENSMMUG00000014677
|
Pre-made viral vector of DNM2 cDNA Clones/ORF Plasmid
DNM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1785 | Pre-made Human DNM2/DYN2/CMT2M siRNA oligo Duplex | 1785 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25751 | Pre-made Rat Dnm2/DYIIAAB siRNA oligo Duplex | 25751 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13430 | Pre-made Mouse Dnm2/Dyn2/Udnm siRNA oligo Duplex | 13430 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713558 | Pre-made Cynomolgus/Rhesus macaque DNM2 siRNA oligo Duplex | 713558 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100788 | Pre-made Cat/Feline DNM2 siRNA oligo Duplex | 101100788 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484949 | Pre-made Dog/Canine DNM2 siRNA oligo Duplex | 484949 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511691 | Pre-made Bovines/Cattle DNM2 siRNA oligo Duplex | 511691 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057627 | Pre-made Equine/Horse DNM2 siRNA oligo Duplex | 100057627 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DNM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6230-Ab | Human | Anti-Human DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6230-Ab | Rat | Anti-Rat DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6230-Ab | Mouse | Anti-Mouse DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6230-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6230-Ab | Cat/Feline | Anti-Cat/Feline DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6230-Ab | Dog/Canine | Anti-Dog/Canine DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6230-Ab | Bovines/Cattle | Anti-Bovines/Cattle DNM2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6230-Ab | Equine/Horse | Anti-Equine/Horse DNM2 monoclonal antibody | mab | | Detail |
DNM2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6230-Ag | Human | Human DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6230-Ag | Rat | Rat DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6230-Ag | Mouse | Mouse DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6230-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6230-Ag | Cat/Feline | Cat/Feline DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6230-Ag | Dog/Canine | Dog/Canine DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6230-Ag | Bovines/Cattle | Bovines/Cattle DNM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6230-Ag | Equine/Horse | Equine/Horse DNM2 recombinant protein | Mammalian cell | Detail |