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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP6105
|
| Target Name |
AKR1C1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1645
|
| Gene ID |
1645 (Homo sapiens)
|
| Target Alternative Names |
2-ALPHA-HSD,20-ALPHA-HSD,20-alpha-hydroxysteroid dehydrogenase (20-alpha-HSD),AKR1C1,Aldo-keto reductase family 1 member C1,C9,Chlordecone reductase homolog HAKRC,DD1,DD1/DD2,DDH,DDH1,Dihydrodiol dehydrogenase 1 (DD1),H-37,HAKRC,HBAB,High-affinity hepatic bile acid-binding protein (HBAB),MBAB
|
| Uniprot Accession |
Q04828
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSG00000187134
|
Pre-made viral vector of AKR1C1 cDNA Clones/ORF Plasmid
AKR1C1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1645 | Pre-made Human AKR1C1/C9/DD1 siRNA oligo Duplex | 1645 | Human | In-vitro grade; in-vivo grade | Detail |
AKR1C1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6105-Ab | Human | Anti-Human AKR1C1 monoclonal antibody | mab | | Detail |
AKR1C1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6105-Ag | Human | Human AKR1C1 recombinant protein | Mammalian cell | Detail |
