Explore CRKL gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
| Target ID |
GM-IP5618
|
| Target Name |
CRKL
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1399
|
| Gene ID |
100050855 (Equus caballus), 101084908 (Felis catus), 12929 (Mus musculus), 1399 (Homo sapiens)
287942 (Rattus norvegicus), 518180 (Bos taurus), 608125 (Canis lupus familiaris), 696584 (Macaca mulatta)
|
| Target Alternative Names |
1110025F07Rik,CRKL,Crk-like protein,Crkl,Crkol,snoop
|
| Uniprot Accession |
P47941,P46109,Q5U2U2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSMUSG00000006134, ENSG00000099942, ENSBTAG00000065402, ENSCAFG00845024825, ENSMMUG00000020478
|
Pre-made viral vector of CRKL cDNA Clones/ORF Plasmid
CRKL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1399 | Pre-made Human CRKL siRNA oligo Duplex | 1399 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287942 | Pre-made Rat Crkl siRNA oligo Duplex | 287942 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12929 | Pre-made Mouse Crkl/Crkol/snoop siRNA oligo Duplex | 12929 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696584 | Pre-made Cynomolgus/Rhesus macaque CRKL siRNA oligo Duplex | 696584 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084908 | Pre-made Cat/Feline CRKL siRNA oligo Duplex | 101084908 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608125 | Pre-made Dog/Canine CRKL siRNA oligo Duplex | 608125 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo518180 | Pre-made Bovines/Cattle CRKL siRNA oligo Duplex | 518180 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050855 | Pre-made Equine/Horse CRKL siRNA oligo Duplex | 100050855 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRKL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP5618-Ab | Human | Anti-Human CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP5618-Ab | Rat | Anti-Rat CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP5618-Ab | Mouse | Anti-Mouse CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP5618-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP5618-Ab | Cat/Feline | Anti-Cat/Feline CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP5618-Ab | Dog/Canine | Anti-Dog/Canine CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP5618-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRKL monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP5618-Ab | Equine/Horse | Anti-Equine/Horse CRKL monoclonal antibody | mab | | Detail |
CRKL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP5618-Ag | Human | Human CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP5618-Ag | Rat | Rat CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP5618-Ag | Mouse | Mouse CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP5618-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP5618-Ag | Cat/Feline | Cat/Feline CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP5618-Ag | Dog/Canine | Dog/Canine CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP5618-Ag | Bovines/Cattle | Bovines/Cattle CRKL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP5618-Ag | Equine/Horse | Equine/Horse CRKL recombinant protein | Mammalian cell | Detail |
