Explore cGAS/CGAS gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont; intracellular signal transduction; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]
| Target ID |
GM-IP4188
|
| Target Name |
cGAS/CGAS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
115004
|
| Gene ID |
100067982 (Equus caballus), 101098056 (Felis catus), 115004 (Homo sapiens), 214763 (Mus musculus)
611033 (Canis lupus familiaris), 682147 (Rattus norvegicus), 717665 (Macaca mulatta), 782472 (Bos taurus)
|
| Target Alternative Names |
2'3'-cGAMP synthase,C6orf150,CGAS,Cgas,Cyclic GMP-AMP synthase,D4,E330016A19Rik,MB21D1,Mab-21 domain-containing protein 1,Mb21d1,cGAMP synthase,cGAS,h-cGAS
|
| Uniprot Accession |
Q8N884,Q8C6L5,E1BGN7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000019809, ENSG00000164430, ENSMUSG00000032344, ENSCAFG00845012039, ENSMMUG00000019606, ENSBTAG00000000892
|
Pre-made viral vector of cGAS/CGAS cDNA Clones/ORF Plasmid
cGAS/CGAS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo115004 | Pre-made Human CGAS/D4/MB21D1 siRNA oligo Duplex | 115004 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo682147 | Pre-made Rat Cgas/Mb21d1 siRNA oligo Duplex | 682147 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo214763 | Pre-made Mouse Cgas/Mb21d1/E330016A19Rik siRNA oligo Duplex | 214763 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717665 | Pre-made Cynomolgus/Rhesus macaque CGAS/MB21D1 siRNA oligo Duplex | 717665 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098056 | Pre-made Cat/Feline CGAS/MB21D1 siRNA oligo Duplex | 101098056 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611033 | Pre-made Dog/Canine CGAS/MB21D1 siRNA oligo Duplex | 611033 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo782472 | Pre-made Bovines/Cattle CGAS/MB21D1 siRNA oligo Duplex | 782472 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067982 | Pre-made Equine/Horse CGAS/MB21D1 siRNA oligo Duplex | 100067982 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
cGAS/CGAS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP4188-Ab | Human | Anti-Human cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP4188-Ab | Rat | Anti-Rat cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP4188-Ab | Mouse | Anti-Mouse cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP4188-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP4188-Ab | Cat/Feline | Anti-Cat/Feline cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP4188-Ab | Dog/Canine | Anti-Dog/Canine cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP4188-Ab | Bovines/Cattle | Anti-Bovines/Cattle cGAS/CGAS monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP4188-Ab | Equine/Horse | Anti-Equine/Horse cGAS/CGAS monoclonal antibody | mab | | Detail |
cGAS/CGAS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP4188-Ag | Human | Human cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP4188-Ag | Rat | Rat cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP4188-Ag | Mouse | Mouse cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP4188-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP4188-Ag | Cat/Feline | Cat/Feline cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP4188-Ag | Dog/Canine | Dog/Canine cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP4188-Ag | Bovines/Cattle | Bovines/Cattle cGAS/CGAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP4188-Ag | Equine/Horse | Equine/Horse cGAS/CGAS recombinant protein | Mammalian cell | Detail |
