Explore FBXO32 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
| Target ID |
GM-IP4180
|
| Target Name |
FBXO32
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
114907
|
| Gene ID |
100057506 (Equus caballus), 101083398 (Felis catus), 114907 (Homo sapiens), 171043 (Rattus norvegicus) 475091 (Canis lupus familiaris), 513776 (Bos taurus), 67731 (Mus musculus), 704804 (Macaca mulatta)
|
| Target Alternative Names |
4833442G10Rik,ATROGIN1,Atrogin-1,Atrogin1,F-box only protein 32,FBXO32,Fbx32,Fbxo32,Gm20361,MAFbx,Muscle atrophy F-box protein (MAFbx)
|
| Uniprot Accession |
Q969P5,Q91Z62,Q2KHT6,Q9CPU7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000016002, ENSG00000156804, ENSCAFG00845009971, ENSBTAG00000016194, ENSMUSG00000022358, ENSMMUG00000023778
|
Pre-made viral vector of FBXO32 cDNA Clones/ORF Plasmid
FBXO32 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo114907 | Pre-made Human FBXO32/Fbx32/MAFbx siRNA oligo Duplex | 114907 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171043 | Pre-made Rat Fbxo32/MAFbx/Atrogin1 siRNA oligo Duplex | 171043 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo67731 | Pre-made Mouse Fbxo32/MAFbx/Gm20361 siRNA oligo Duplex | 67731 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704804 | Pre-made Cynomolgus/Rhesus macaque FBXO32 siRNA oligo Duplex | 704804 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083398 | Pre-made Cat/Feline FBXO32 siRNA oligo Duplex | 101083398 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475091 | Pre-made Dog/Canine FBXO32 siRNA oligo Duplex | 475091 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513776 | Pre-made Bovines/Cattle FBXO32 siRNA oligo Duplex | 513776 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057506 | Pre-made Equine/Horse FBXO32 siRNA oligo Duplex | 100057506 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FBXO32 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP4180-Ab | Human | Anti-Human FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP4180-Ab | Rat | Anti-Rat FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP4180-Ab | Mouse | Anti-Mouse FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP4180-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP4180-Ab | Cat/Feline | Anti-Cat/Feline FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP4180-Ab | Dog/Canine | Anti-Dog/Canine FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP4180-Ab | Bovines/Cattle | Anti-Bovines/Cattle FBXO32 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP4180-Ab | Equine/Horse | Anti-Equine/Horse FBXO32 monoclonal antibody | mab | | Detail |
FBXO32 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP4180-Ag | Human | Human FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP4180-Ag | Rat | Rat FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP4180-Ag | Mouse | Mouse FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP4180-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP4180-Ag | Cat/Feline | Cat/Feline FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP4180-Ag | Dog/Canine | Dog/Canine FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP4180-Ag | Bovines/Cattle | Bovines/Cattle FBXO32 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP4180-Ag | Equine/Horse | Equine/Horse FBXO32 recombinant protein | Mammalian cell | Detail |