Explore LIAS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Aug 2020]
| Target ID |
GM-IP3903
|
| Target Name |
LIAS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11019
|
| Gene ID |
100055115 (Equus caballus), 101083674 (Felis catus), 11019 (Homo sapiens), 305348 (Rattus norvegicus)
479108 (Canis lupus familiaris), 530865 (Bos taurus), 699244 (Macaca mulatta), 79464 (Mus musculus)
|
| Target Alternative Names |
2900022L22Rik,4933425M12Rik,7a5ex,HGCLAS,HUSSY-01,LAS,LIAS,LIP1,LS,Lias,Lip-syn),Lipoate synthase (LS,Lipoic acid synthase,Lipoyl synthase,PDHLD,lip-syn,mitochondrial
|
| Uniprot Accession |
O43766,Q5XIH4,Q5BIP7,Q99M04
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000015796, ENSG00000121897, ENSCAFG00845004611, ENSBTAG00000014520, ENSMMUG00000013851, ENSMUSG00000029199
|
Pre-made viral vector of LIAS cDNA Clones/ORF Plasmid
LIAS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11019 | Pre-made Human LIAS/LS/LAS siRNA oligo Duplex | 11019 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305348 | Pre-made Rat Lias siRNA oligo Duplex | 305348 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79464 | Pre-made Mouse Lias/LS/7a5ex siRNA oligo Duplex | 79464 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699244 | Pre-made Cynomolgus/Rhesus macaque LIAS siRNA oligo Duplex | 699244 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083674 | Pre-made Cat/Feline LIAS siRNA oligo Duplex | 101083674 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479108 | Pre-made Dog/Canine LIAS siRNA oligo Duplex | 479108 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530865 | Pre-made Bovines/Cattle LIAS siRNA oligo Duplex | 530865 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055115 | Pre-made Equine/Horse LIAS siRNA oligo Duplex | 100055115 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LIAS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP3903-Ab | Human | Anti-Human LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP3903-Ab | Rat | Anti-Rat LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP3903-Ab | Mouse | Anti-Mouse LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP3903-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP3903-Ab | Cat/Feline | Anti-Cat/Feline LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP3903-Ab | Dog/Canine | Anti-Dog/Canine LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP3903-Ab | Bovines/Cattle | Anti-Bovines/Cattle LIAS monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP3903-Ab | Equine/Horse | Anti-Equine/Horse LIAS monoclonal antibody | mab | | Detail |
LIAS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP3903-Ag | Human | Human LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP3903-Ag | Rat | Rat LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP3903-Ag | Mouse | Mouse LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP3903-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP3903-Ag | Cat/Feline | Cat/Feline LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP3903-Ag | Dog/Canine | Dog/Canine LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP3903-Ag | Bovines/Cattle | Bovines/Cattle LIAS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP3903-Ag | Equine/Horse | Equine/Horse LIAS recombinant protein | Mammalian cell | Detail |
