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Target
sublocation: Introcelluar Protein.
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]
| Target ID |
GM-IP3736
|
| Target Name |
TRAF3IP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10758
|
| Gene ID |
100066812 (Equus caballus), 101085125 (Felis catus), 103213 (Mus musculus), 10758 (Homo sapiens) 361857 (Rattus norvegicus), 475031 (Canis lupus familiaris), 616801 (Bos taurus), 697530 (Macaca mulatta)
|
| Target Alternative Names |
ACT1,Act1,Adapter protein CIKS,C6ORF4,C6orf2,C6orf4,C6orf5,C6orf6,CANDF8,CIKS,Connection to IKK and SAPK/JNK,E3 ubiquitin ligase TRAF3IP2,E3 ubiquitin-protein ligase CIKS,Nuclear factor NF-kappa-B activator 1 (ACT1),PSORS13,RGD1304768,TRAF3-interacting protein 2,TRAF3IP2,Traf3ip2
|
| Uniprot Accession |
Q8N7N6,O43734
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
Prostate Cancer
|
| Gene Ensembl |
ENSECAG00000000591, ENSMUSG00000019842, ENSG00000056972, ENSCAFG00845017420, ENSBTAG00000008600, ENSMMUG00000002174
|
Pre-made viral vector of TRAF3IP2 cDNA Clones/ORF Plasmid
TRAF3IP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10758 | Pre-made Human TRAF3IP2/ACT1/CIKS siRNA oligo Duplex | 10758 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361857 | Pre-made Rat Traf3ip2/RGD1304768 siRNA oligo Duplex | 361857 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo103213 | Pre-made Mouse Traf3ip2/Act1/CIKS siRNA oligo Duplex | 103213 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697530 | Pre-made Cynomolgus/Rhesus macaque TRAF3IP2 siRNA oligo Duplex | 697530 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085125 | Pre-made Cat/Feline TRAF3IP2 siRNA oligo Duplex | 101085125 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475031 | Pre-made Dog/Canine TRAF3IP2 siRNA oligo Duplex | 475031 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616801 | Pre-made Bovines/Cattle TRAF3IP2/C6ORF4 siRNA oligo Duplex | 616801 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066812 | Pre-made Equine/Horse TRAF3IP2 siRNA oligo Duplex | 100066812 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRAF3IP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP3736-Ab | Human | Anti-Human TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP3736-Ab | Rat | Anti-Rat TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP3736-Ab | Mouse | Anti-Mouse TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP3736-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP3736-Ab | Cat/Feline | Anti-Cat/Feline TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP3736-Ab | Dog/Canine | Anti-Dog/Canine TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP3736-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRAF3IP2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP3736-Ab | Equine/Horse | Anti-Equine/Horse TRAF3IP2 monoclonal antibody | mab | | Detail |
TRAF3IP2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP3736-Ag | Human | Human TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP3736-Ag | Rat | Rat TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP3736-Ag | Mouse | Mouse TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP3736-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP3736-Ag | Cat/Feline | Cat/Feline TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP3736-Ag | Dog/Canine | Dog/Canine TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP3736-Ag | Bovines/Cattle | Bovines/Cattle TRAF3IP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP3736-Ag | Equine/Horse | Equine/Horse TRAF3IP2 recombinant protein | Mammalian cell | Detail |