Explore NPRL2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Enables GTPase activator activity. Involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and negative regulation of kinase activity. Part of GATOR1 complex. Is active in lysosomal membrane. Implicated in familial focal epilepsy with variable foci 2. [provided by Alliance of Genome Resources, Feb 2025]
| Target ID |
GM-IP3687
|
| Target Name |
NPRL2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10641
|
| Gene ID |
100061750 (Equus caballus), 101095158 (Felis catus), 10641 (Homo sapiens), 363138 (Rattus norvegicus)
476614 (Canis lupus familiaris), 508487 (Bos taurus), 56032 (Mus musculus), 701924 (Macaca mulatta)
|
| Target Alternative Names |
2810446G01Rik,FFEVF2,G21,GATOR1 complex protein NPRL2,Gene 21 protein (G21 protein),NPR2,NPR2L,NPRL2,Nitrogen permease regulator 2-like protein (NPR2-like protein),Nprl2,TUSC4,Tumor suppressor candidate 4,Tusc4
|
| Uniprot Accession |
Q8WTW4,Q5E9U9,Q9WUE4
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSG00000114388, ENSCAFG00845021164, ENSBTAG00000019161, ENSMUSG00000010057, ENSMMUG00000007013
|
Pre-made viral vector of NPRL2 cDNA Clones/ORF Plasmid
NPRL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10641 | Pre-made Human NPRL2/NPR2/NPR2L siRNA oligo Duplex | 10641 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363138 | Pre-made Rat Nprl2/Tusc4 siRNA oligo Duplex | 363138 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56032 | Pre-made Mouse Nprl2/G21/NPR2L siRNA oligo Duplex | 56032 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701924 | Pre-made Cynomolgus/Rhesus macaque NPRL2/TUSC4 siRNA oligo Duplex | 701924 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095158 | Pre-made Cat/Feline NPRL2 siRNA oligo Duplex | 101095158 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476614 | Pre-made Dog/Canine NPRL2/TUSC4 siRNA oligo Duplex | 476614 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508487 | Pre-made Bovines/Cattle NPRL2/TUSC4 siRNA oligo Duplex | 508487 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061750 | Pre-made Equine/Horse NPRL2 siRNA oligo Duplex | 100061750 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPRL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP3687-Ab | Human | Anti-Human NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP3687-Ab | Rat | Anti-Rat NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP3687-Ab | Mouse | Anti-Mouse NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP3687-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP3687-Ab | Cat/Feline | Anti-Cat/Feline NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP3687-Ab | Dog/Canine | Anti-Dog/Canine NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP3687-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPRL2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP3687-Ab | Equine/Horse | Anti-Equine/Horse NPRL2 monoclonal antibody | mab | | Detail |
NPRL2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP3687-Ag | Human | Human NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP3687-Ag | Rat | Rat NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP3687-Ag | Mouse | Mouse NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP3687-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP3687-Ag | Cat/Feline | Cat/Feline NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP3687-Ag | Dog/Canine | Dog/Canine NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP3687-Ag | Bovines/Cattle | Bovines/Cattle NPRL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP3687-Ag | Equine/Horse | Equine/Horse NPRL2 recombinant protein | Mammalian cell | Detail |
