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Target
sublocation: Introcelluar Protein.
This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
| Target ID |
GM-IP3102
|
| Target Name |
DUX4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
100288687
|
| Gene ID |
100288687 (Homo sapiens), 100429788 (Macaca mulatta)
|
| Target Alternative Names |
DUX4,DUX4L,Double homeobox protein 10,Double homeobox protein 4
|
| Uniprot Accession |
Q9UBX2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSG00000260596
|
DUX4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo100288687 | Pre-made Human DUX4/DUX4L siRNA oligo Duplex | 100288687 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100429788 | Pre-made Cynomolgus/Rhesus macaque DUX4 siRNA oligo Duplex | 100429788 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
DUX4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP3102-Ab | Human | Anti-Human DUX4 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP3102-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DUX4 monoclonal antibody | mab | | Detail |
DUX4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP3102-Ag | Human | Human DUX4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP3102-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DUX4 recombinant protein | Mammalian cell | Detail |
