Explore LPIN1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017]
| Target ID |
GM-IP2578
|
| Target Name |
LPIN1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
23175
|
| Gene ID |
100072273 (Equus caballus), 101085623 (Felis catus), 14245 (Mus musculus), 23175 (Homo sapiens) 313977 (Rattus norvegicus), 475670 (Canis lupus familiaris), 537224 (Bos taurus), 697682 (Macaca mulatta)
|
| Target Alternative Names |
LPIN1,Lipin-1,Lipin1,Lpin1,PAP1,Phosphatidate phosphatase LPIN1,fld,lipin1
|
| Uniprot Accession |
Q91ZP3,Q14693
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Metabolic pathways, Alcoholic liver disease, Glycerophospholipid metabolism
|
| Gene Ensembl |
ENSECAG00000011239, ENSMUSG00000020593, ENSG00000134324, ENSCAFG00845028736, ENSBTAG00000007689, ENSMMUG00000021672
|
LPIN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23175 | Pre-made Human LPIN1/PAP1 siRNA oligo Duplex | 23175 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313977 | Pre-made Rat Lpin1 siRNA oligo Duplex | 313977 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14245 | Pre-made Mouse Lpin1/fld/Lipin1 siRNA oligo Duplex | 14245 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697682 | Pre-made Cynomolgus/Rhesus macaque LPIN1 siRNA oligo Duplex | 697682 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085623 | Pre-made Cat/Feline LPIN1 siRNA oligo Duplex | 101085623 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475670 | Pre-made Dog/Canine LPIN1 siRNA oligo Duplex | 475670 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo537224 | Pre-made Bovines/Cattle LPIN1/lipin1 siRNA oligo Duplex | 537224 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072273 | Pre-made Equine/Horse LPIN1 siRNA oligo Duplex | 100072273 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LPIN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2578-Ab | Human | Anti-Human LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2578-Ab | Rat | Anti-Rat LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2578-Ab | Mouse | Anti-Mouse LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2578-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2578-Ab | Cat/Feline | Anti-Cat/Feline LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2578-Ab | Dog/Canine | Anti-Dog/Canine LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2578-Ab | Bovines/Cattle | Anti-Bovines/Cattle LPIN1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2578-Ab | Equine/Horse | Anti-Equine/Horse LPIN1 monoclonal antibody | mab | | Detail |
LPIN1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2578-Ag | Human | Human LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2578-Ag | Rat | Rat LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2578-Ag | Mouse | Mouse LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2578-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2578-Ag | Cat/Feline | Cat/Feline LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2578-Ag | Dog/Canine | Dog/Canine LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2578-Ag | Bovines/Cattle | Bovines/Cattle LPIN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2578-Ag | Equine/Horse | Equine/Horse LPIN1 recombinant protein | Mammalian cell | Detail |