Explore KMT2D gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
| Target ID |
GM-IP2567
|
| Target Name |
KMT2D
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8085
|
| Gene ID |
100058932 (Equus caballus), 100362634 (Rattus norvegicus), 101095268 (Felis catus), 381022 (Mus musculus)
486558 (Canis lupus familiaris), 506805 (Bos taurus), 710795 (Macaca mulatta), 8085 (Homo sapiens)
|
| Target Alternative Names |
AAD10,ALL1-related protein,ALR,BCAHH,C430014K11Rik,CAGL114,Histone-lysine N-methyltransferase 2D,KABUK1,KMS,KMT2B,KMT2D,Kmt2d,Lysine N-methyltransferase 2D,MLL2,MLL4,Mll2,Mll4,Myeloid/lymphoid or mixed-lineage leukemia protein 2,TNRC21,bapa
|
| Uniprot Accession |
Q6PDK2,O14686
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Cushing syndrome
|
| Gene Ensembl |
ENSECAG00000017946, ENSMUSG00000048154, ENSCAFG00845021787, ENSBTAG00000014429, ENSMMUG00000015718, ENSG00000167548
|
| Target Classification |
Tumor-associated antigen (TAA)
|
KMT2D siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8085 | Pre-made Human KMT2D/ALR/KMS siRNA oligo Duplex | 8085 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100362634 | Pre-made Rat Kmt2d/Mll2 siRNA oligo Duplex | 100362634 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo381022 | Pre-made Mouse Kmt2d/ALR/Mll2 siRNA oligo Duplex | 381022 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710795 | Pre-made Cynomolgus/Rhesus macaque KMT2D/MLL2 siRNA oligo Duplex | 710795 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095268 | Pre-made Cat/Feline KMT2D/MLL2 siRNA oligo Duplex | 101095268 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486558 | Pre-made Dog/Canine KMT2D/MLL2 siRNA oligo Duplex | 486558 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506805 | Pre-made Bovines/Cattle KMT2D/MLL2 siRNA oligo Duplex | 506805 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058932 | Pre-made Equine/Horse KMT2D/ALR siRNA oligo Duplex | 100058932 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KMT2D antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2567-Ab | Human | Anti-Human KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2567-Ab | Rat | Anti-Rat KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2567-Ab | Mouse | Anti-Mouse KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2567-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2567-Ab | Cat/Feline | Anti-Cat/Feline KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2567-Ab | Dog/Canine | Anti-Dog/Canine KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2567-Ab | Bovines/Cattle | Anti-Bovines/Cattle KMT2D monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2567-Ab | Equine/Horse | Anti-Equine/Horse KMT2D monoclonal antibody | mab | | Detail |
KMT2D recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2567-Ag | Human | Human KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2567-Ag | Rat | Rat KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2567-Ag | Mouse | Mouse KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2567-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2567-Ag | Cat/Feline | Cat/Feline KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2567-Ag | Dog/Canine | Dog/Canine KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2567-Ag | Bovines/Cattle | Bovines/Cattle KMT2D recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2567-Ag | Equine/Horse | Equine/Horse KMT2D recombinant protein | Mammalian cell | Detail |
