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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]
| Target ID |
GM-IP2239
|
| Target Name |
UGT2B7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7364
|
| Gene ID |
708989 (Macaca mulatta), 7364 (Homo sapiens)
|
| Target Alternative Names |
3,4-catechol estrogen-specific UDPGT,UDP-glucuronosyltransferase 2B7,UDP-glucuronosyltransferase 2B9 (UDPGT 2B9),UDPGT 2B7,UDPGT 2B9,UDPGT2B7,UDPGTH2,UDPGTh-2,UGT2B7,UGT2B9
|
| Uniprot Accession |
P16662
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Steroid hormone biosynthesis, Pentose and glucuronate interconversions, Bile secretion, Chemical carcinogenesis - DNA adducts, Chemical carcinogenesis - receptor activation, Ascorbate and aldarate metabolism, Retinol metabolism, Porphyrin metabolism, Drug metabolism - cytochrome P450
|
| Gene Ensembl |
ENSG00000171234
|
UGT2B7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7364 | Pre-made Human UGT2B7/UGT2B9/UDPGTH2 siRNA oligo Duplex | 7364 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708989 | Pre-made Cynomolgus/Rhesus macaque UGT2B7 siRNA oligo Duplex | 708989 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
UGT2B7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2239-Ab | Human | Anti-Human UGT2B7 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2239-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque UGT2B7 monoclonal antibody | mab | | Detail |
UGT2B7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2239-Ag | Human | Human UGT2B7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2239-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque UGT2B7 recombinant protein | Mammalian cell | Detail |
