Explore SETDB1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
| Target ID |
GM-IP1618
|
| Target Name |
SETDB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9869
|
| Gene ID |
100059254 (Equus caballus), 100138100 (Bos taurus), 101094118 (Felis catus), 483186 (Canis lupus familiaris)
689883 (Rattus norvegicus), 716141 (Macaca mulatta), 84505 (Mus musculus), 9869 (Homo sapiens)
|
| Target Alternative Names |
SETDB1,Setdb1,ESET,KMT1E,mKIAA0067,KG1T,TDRD21,H3-K9-HMTase4
|
| Uniprot Accession |
O88974,Q15047
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Signaling pathways regulating pluripotency of stem cells
|
| Gene Ensembl |
ENSECAG00000023954, ENSBTAG00000000098, ENSCAFG00845020216, ENSMMUG00000023235, ENSMUSG00000015697, ENSG00000143379
|
| Target Classification |
|
Pre-made viral vector of SETDB1 cDNA Clones/ORF Plasmid
SETDB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9869 | Pre-made Human SETDB1/ESET/KG1T siRNA oligo Duplex | 9869 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo689883 | Pre-made Rat Setdb1 siRNA oligo Duplex | 689883 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84505 | Pre-made Mouse Setdb1/ESET/KMT1E siRNA oligo Duplex | 84505 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716141 | Pre-made Cynomolgus/Rhesus macaque SETDB1 siRNA oligo Duplex | 716141 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094118 | Pre-made Cat/Feline SETDB1 siRNA oligo Duplex | 101094118 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483186 | Pre-made Dog/Canine SETDB1 siRNA oligo Duplex | 483186 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100138100 | Pre-made Bovines/Cattle SETDB1 siRNA oligo Duplex | 100138100 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059254 | Pre-made Equine/Horse SETDB1 siRNA oligo Duplex | 100059254 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SETDB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP1618-Ab | Human | Anti-Human SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP1618-Ab | Rat | Anti-Rat SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP1618-Ab | Mouse | Anti-Mouse SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP1618-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP1618-Ab | Cat/Feline | Anti-Cat/Feline SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP1618-Ab | Dog/Canine | Anti-Dog/Canine SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP1618-Ab | Bovines/Cattle | Anti-Bovines/Cattle SETDB1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP1618-Ab | Equine/Horse | Anti-Equine/Horse SETDB1 monoclonal antibody | mab | | Detail |
SETDB1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP1618-Ag | Human | Human SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP1618-Ag | Rat | Rat SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP1618-Ag | Mouse | Mouse SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP1618-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP1618-Ag | Cat/Feline | Cat/Feline SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP1618-Ag | Dog/Canine | Dog/Canine SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP1618-Ag | Bovines/Cattle | Bovines/Cattle SETDB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP1618-Ag | Equine/Horse | Equine/Horse SETDB1 recombinant protein | Mammalian cell | Detail |
