Explore RRM2B/p53R2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
| Target ID |
GM-IP1559
|
| Target Name |
RRM2B/p53R2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
50484
|
| Gene ID |
100062030 (Equus caballus), 101099777 (Felis catus), 299976 (Rattus norvegicus), 382985 (Mus musculus)
481988 (Canis lupus familiaris), 50484 (Homo sapiens), 528960 (Bos taurus), 707062 (Macaca mulatta)
|
| Target Alternative Names |
MTDPS8A,MTDPS8B,P53R2,RCDFRD,RRM2B,Ribonucleoside-diphosphate reductase subunit M2 B,Rrm2b,TP53-inducible ribonucleotide reductase M2 B,p53-inducible ribonucleotide reductase small subunit 2-like protein (p53R2),p53R2
|
| Uniprot Accession |
Q6PEE3,Q7LG56
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, p53 signaling pathway
|
| Gene Ensembl |
ENSECAG00000006166, ENSMUSG00000022292, ENSG00000048392, ENSBTAG00000021208
|
| Target Classification |
|
Pre-made viral vector of RRM2B/p53R2 cDNA Clones/ORF Plasmid
RRM2B/p53R2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo50484 | Pre-made Human RRM2B/P53R2/RCDFRD siRNA oligo Duplex | 50484 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo299976 | Pre-made Rat Rrm2b siRNA oligo Duplex | 299976 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo382985 | Pre-made Mouse Rrm2b/p53R2 siRNA oligo Duplex | 382985 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707062 | Pre-made Cynomolgus/Rhesus macaque RRM2B siRNA oligo Duplex | 707062 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099777 | Pre-made Cat/Feline RRM2B siRNA oligo Duplex | 101099777 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481988 | Pre-made Dog/Canine RRM2B siRNA oligo Duplex | 481988 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528960 | Pre-made Bovines/Cattle RRM2B siRNA oligo Duplex | 528960 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062030 | Pre-made Equine/Horse RRM2B siRNA oligo Duplex | 100062030 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RRM2B/p53R2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP1559-Ab | Human | Anti-Human RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP1559-Ab | Rat | Anti-Rat RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP1559-Ab | Mouse | Anti-Mouse RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP1559-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP1559-Ab | Cat/Feline | Anti-Cat/Feline RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP1559-Ab | Dog/Canine | Anti-Dog/Canine RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP1559-Ab | Bovines/Cattle | Anti-Bovines/Cattle RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP1559-Ab | Equine/Horse | Anti-Equine/Horse RRM2B/p53R2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RRM2B/p53R2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP1559-Ag | Human | Human RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP1559-Ag | Rat | Rat RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP1559-Ag | Mouse | Mouse RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP1559-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP1559-Ag | Cat/Feline | Cat/Feline RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP1559-Ag | Dog/Canine | Dog/Canine RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP1559-Ag | Bovines/Cattle | Bovines/Cattle RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP1559-Ag | Equine/Horse | Equine/Horse RRM2B/p53R2 recombinant protein | Mammalian cell | Detail |
