AMPK Alpha 2/PRKAA2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore AMPK Alpha 2/PRKAA2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

Target ID GM-IP1444
Target Name AMPK Alpha 2/PRKAA2
Gene Group ldentifer
（Target Gene ID in Homo species) 		5563
Gene ID 100034159 (Equus caballus), 101096000 (Felis catus), 108079 (Mus musculus), 489571 (Canis lupus familiaris)
538954 (Bos taurus), 5563 (Homo sapiens), 717703 (Macaca mulatta), 78975 (Rattus norvegicus)
Target Alternative Names 2310008I11Rik,5'-AMP-activated protein kinase catalytic subunit alpha-2,A830082D05,AMPK,AMPK Alpha 2,AMPK subunit alpha-2,AMPK2,AMPKa2,AMPKalpha2,Acetyl-CoA carboxylase kinase (ACACA kinase),Ampk,Ampka2,Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase),PRKAA,PRKAA2,Prkaa2
Uniprot Accession Q8BRK8,P54646,Q09137
Protein Sub-location Introcelluar Protein
Disease from KEGG FoxO signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Tight junction, Adipocytokine signaling pathway, Oxytocin signaling pathway, Insulin resistance, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis
Gene Ensembl ENSECAG00000012967, ENSMUSG00000028518, ENSCAFG00845013807, ENSBTAG00000018747, ENSG00000162409, ENSMMUG00000010406
Target Classification Kinase


Pre-made viral vector of AMPK Alpha 2/PRKAA2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001356Human PRKAA2/AMPK/AMPK2 Lentivirus plasmidNM_006252.35563HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP001898Human PRKAA2/AMPK/AMPK2 Lentivirus plasmidNM_006252.35563HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005643Human PRKAA2/AMPK/AMPK2 Lentivirus plasmidNM_006252.35563HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPh-282Human PRKAA2/AMPK/AMPK2 Adenovirus plasmidNM_006252.35563HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP001356Human PRKAA2/AMPK/AMPK2 Lentivirus particleNM_006252.35563HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001898Human PRKAA2/AMPK/AMPK2 Lentivirus particleNM_006252.35563HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005643Human PRKAA2/AMPK/AMPK2 Lentivirus particleNM_006252.35563HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPh-282Human PRKAA2/AMPK/AMPK2 Adenovirus particleNM_006252.35563HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMAAV000081Rat Prkaa2/Ampk/Ampka2 Adeno-associate virus(AAV) plasmidNM_023991.178975RatAdeno-associate virus(AAV) plasmidNull3xflag (C-Terminal)CMVDetail
vGMAAV000081Rat Prkaa2/Ampk/Ampka2 Adeno-associate virus(AAV) particleNM_023991.178975RatAdeno-associate virus(AAV) particleNull3xflag (C-Terminal)CMVDetail
pGMAD000699Mouse Prkaa2/2310008I11Rik/A830082D05 Adenovirus plasmidNM_178143.2108079MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMAAV001419Mouse Prkaa2/2310008I11Rik/A830082D05 Adeno-associate virus(AAV) plasmidNM_178143108079MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CAGDetail
pGMLPm004043Mouse Prkaa2/2310008I11Rik/A830082D05 Lentivirus plasmidNM_178143108079MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000699Mouse Prkaa2/2310008I11Rik/A830082D05 Adenovirus particleNM_178143.2108079MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
vGMAAV001419Mouse Prkaa2/2310008I11Rik/A830082D05 Adeno-associate virus(AAV) particleNM_178143108079MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CAGDetail
vGMLPm004043Mouse Prkaa2/2310008I11Rik/A830082D05 Lentivirus particleNM_178143108079MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


AMPK Alpha 2/PRKAA2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5563Pre-made Human PRKAA2/AMPK/AMPK2 siRNA oligo Duplex5563HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo78975Pre-made Rat Prkaa2/Ampk/Ampka2 siRNA oligo Duplex78975RatIn-vitro grade; in-vivo gradeDetail
pGMoligo108079Pre-made Mouse Prkaa2/A830082D05/AMPKalpha2 siRNA oligo Duplex108079MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo717703Pre-made Cynomolgus/Rhesus macaque PRKAA2 siRNA oligo Duplex717703Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101096000Pre-made Cat/Feline PRKAA2 siRNA oligo Duplex101096000Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo489571Pre-made Dog/Canine PRKAA2 siRNA oligo Duplex489571Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo538954Pre-made Bovines/Cattle PRKAA2 siRNA oligo Duplex538954Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100034159Pre-made Equine/Horse PRKAA2 siRNA oligo Duplex100034159Equine/HorseIn-vitro grade; in-vivo gradeDetail


AMPK Alpha 2/PRKAA2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP1444-AbHumanAnti-Human AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-rg-IP1444-AbRatAnti-Rat AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-mg-IP1444-AbMouseAnti-Mouse AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-cynog-IP1444-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-felg-IP1444-AbCat/FelineAnti-Cat/Feline AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-cang-IP1444-AbDog/CanineAnti-Dog/Canine AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-bovg-IP1444-AbBovines/CattleAnti-Bovines/Cattle AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail
GM-Tg-equg-IP1444-AbEquine/HorseAnti-Equine/Horse AMPK Alpha 2/PRKAA2 monoclonal antibodymabDetail


AMPK Alpha 2/PRKAA2 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP1444-AgHumanHuman AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP1444-AgRatRat AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP1444-AgMouseMouse AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP1444-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP1444-AgCat/FelineCat/Feline AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP1444-AgDog/CanineDog/Canine AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP1444-AgBovines/CattleBovines/Cattle AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail
GM-Tg-equg-IP1444-AgEquine/HorseEquine/Horse AMPK Alpha 2/PRKAA2 recombinant proteinMammalian cellDetail