Explore KMT2B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP13905
|
| Target Name |
KMT2B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9757
|
| Gene ID |
100059802 (Equus caballus), 100688666 (Canis lupus familiaris), 101098760 (Felis catus), 102550344 (Rattus norvegicus)
718835 (Macaca mulatta), 75410 (Mus musculus), 785776 (Bos taurus), 9757 (Homo sapiens)
|
| Target Alternative Names |
2610014H22Rik,CXXC10,DYT28,HRX2,Histone-lysine N-methyltransferase 2B,KMT2B,Kmt2b,Lysine N-methyltransferase 2B,MLL1B,MLL2,MLL4,MRD68,Mll2,Mll4,Myeloid/lymphoid or mixed-lineage leukemia protein 4,RGD1308331,TRX2,Trithorax homolog 2,WBP-7,WBP7,WW domain-binding protein 7 (WBP-7),Wbp7,mKIAA0304
|
| Uniprot Accession |
O08550,Q9UMN6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000007605, ENSCAFG00845001587, ENSMMUG00000002381, ENSMUSG00000006307, ENSBTAG00000002763, ENSG00000272333
|
KMT2B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9757 | Pre-made Human KMT2B/HRX2/MLL2 siRNA oligo Duplex | 9757 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102550344 | Pre-made Rat Kmt2b/Mll4/Wbp7 siRNA oligo Duplex | 102550344 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo75410 | Pre-made Mouse Kmt2b/Mll2/Wbp7 siRNA oligo Duplex | 75410 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718835 | Pre-made Cynomolgus/Rhesus macaque KMT2B/MLL4 siRNA oligo Duplex | 718835 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098760 | Pre-made Cat/Feline KMT2B siRNA oligo Duplex | 101098760 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100688666 | Pre-made Dog/Canine KMT2B/MLL4 siRNA oligo Duplex | 100688666 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo785776 | Pre-made Bovines/Cattle KMT2B siRNA oligo Duplex | 785776 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059802 | Pre-made Equine/Horse KMT2B siRNA oligo Duplex | 100059802 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KMT2B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13905-Ab | Human | Anti-Human KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13905-Ab | Rat | Anti-Rat KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13905-Ab | Mouse | Anti-Mouse KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13905-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13905-Ab | Cat/Feline | Anti-Cat/Feline KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13905-Ab | Dog/Canine | Anti-Dog/Canine KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13905-Ab | Bovines/Cattle | Anti-Bovines/Cattle KMT2B monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13905-Ab | Equine/Horse | Anti-Equine/Horse KMT2B monoclonal antibody | mab | | Detail |
KMT2B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13905-Ag | Human | Human KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13905-Ag | Rat | Rat KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13905-Ag | Mouse | Mouse KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13905-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13905-Ag | Cat/Feline | Cat/Feline KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13905-Ag | Dog/Canine | Dog/Canine KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13905-Ag | Bovines/Cattle | Bovines/Cattle KMT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13905-Ag | Equine/Horse | Equine/Horse KMT2B recombinant protein | Mammalian cell | Detail |
