Explore API5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
| Target ID |
GM-IP13153
|
| Target Name |
API5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8539
|
| Gene ID |
100050009 (Equus caballus), 101081754 (Felis catus), 11800 (Mus musculus), 362170 (Rattus norvegicus)
483413 (Canis lupus familiaris), 538968 (Bos taurus), 716346 (Macaca mulatta), 8539 (Homo sapiens)
|
| Target Alternative Names |
AAC-11,AAC11,API-5,API5,Antiapoptosis clone 11 protein (AAC-11),Api5,Apoptosis inhibitor 5,Cell migration-inducing gene 8 protein,Fibroblast growth factor 2-interacting factor (FIF),Protein XAGL
|
| Uniprot Accession |
O35841,Q9BZZ5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000047216, ENSMUSG00000027193, ENSCAFG00845019464, ENSBTAG00000014474, ENSMMUG00000008827, ENSG00000166181
|
Pre-made viral vector of API5 cDNA Clones/ORF Plasmid
API5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8539 | Pre-made Human API5/AAC11/AAC-11 siRNA oligo Duplex | 8539 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362170 | Pre-made Rat Api5 siRNA oligo Duplex | 362170 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11800 | Pre-made Mouse Api5/API-5/AAC-11 siRNA oligo Duplex | 11800 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716346 | Pre-made Cynomolgus/Rhesus macaque API5 siRNA oligo Duplex | 716346 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081754 | Pre-made Cat/Feline API5 siRNA oligo Duplex | 101081754 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483413 | Pre-made Dog/Canine API5 siRNA oligo Duplex | 483413 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538968 | Pre-made Bovines/Cattle API5 siRNA oligo Duplex | 538968 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050009 | Pre-made Equine/Horse API5 siRNA oligo Duplex | 100050009 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
API5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13153-Ab | Human | Anti-Human API5 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13153-Ab | Rat | Anti-Rat API5 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13153-Ab | Mouse | Anti-Mouse API5 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13153-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque API5 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13153-Ab | Cat/Feline | Anti-Cat/Feline API5 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13153-Ab | Dog/Canine | Anti-Dog/Canine API5 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13153-Ab | Bovines/Cattle | Anti-Bovines/Cattle API5 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13153-Ab | Equine/Horse | Anti-Equine/Horse API5 monoclonal antibody | mab | | Detail |
API5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13153-Ag | Human | Human API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13153-Ag | Rat | Rat API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13153-Ag | Mouse | Mouse API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13153-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13153-Ag | Cat/Feline | Cat/Feline API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13153-Ag | Dog/Canine | Dog/Canine API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13153-Ag | Bovines/Cattle | Bovines/Cattle API5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13153-Ag | Equine/Horse | Equine/Horse API5 recombinant protein | Mammalian cell | Detail |
