Explore ESPN gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. [provided by RefSeq, Nov 2009]
| Target ID |
GM-IP12730
|
| Target Name |
ESPN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
83715
|
| Gene ID |
100147497 (Equus caballus), 101094115 (Felis catus), 104976499 (Bos taurus), 489631 (Canis lupus familiaris)
56226 (Mus musculus), 56227 (Rattus norvegicus), 722532 (Macaca mulatta), 83715 (Homo sapiens)
|
| Target Alternative Names |
Autosomal recessive deafness type 36 protein,DFNB36,ESPN,Ectoplasmic specialization protein,Espin,Espn,Je,LP2654,USH1M,je
|
| Uniprot Accession |
Q9ET47,Q63618,B1AK53
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000020345, ENSBTAG00000006515, ENSCAFG00845024302, ENSMUSG00000028943, ENSMMUG00000023676, ENSG00000187017
|
ESPN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo83715 | Pre-made Human ESPN/USH1M/DFNB36 siRNA oligo Duplex | 83715 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56227 | Pre-made Rat Espn/Je siRNA oligo Duplex | 56227 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56226 | Pre-made Mouse Espn/je siRNA oligo Duplex | 56226 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722532 | Pre-made Cynomolgus/Rhesus macaque ESPN siRNA oligo Duplex | 722532 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094115 | Pre-made Cat/Feline ESPN siRNA oligo Duplex | 101094115 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489631 | Pre-made Dog/Canine ESPN siRNA oligo Duplex | 489631 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo104976499 | Pre-made Bovines/Cattle ESPN siRNA oligo Duplex | 104976499 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147497 | Pre-made Equine/Horse ESPN siRNA oligo Duplex | 100147497 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ESPN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12730-Ab | Human | Anti-Human ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12730-Ab | Rat | Anti-Rat ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12730-Ab | Mouse | Anti-Mouse ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12730-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12730-Ab | Cat/Feline | Anti-Cat/Feline ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12730-Ab | Dog/Canine | Anti-Dog/Canine ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12730-Ab | Bovines/Cattle | Anti-Bovines/Cattle ESPN monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12730-Ab | Equine/Horse | Anti-Equine/Horse ESPN monoclonal antibody | mab | | Detail |
ESPN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12730-Ag | Human | Human ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12730-Ag | Rat | Rat ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12730-Ag | Mouse | Mouse ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12730-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12730-Ag | Cat/Feline | Cat/Feline ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12730-Ag | Dog/Canine | Dog/Canine ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12730-Ag | Bovines/Cattle | Bovines/Cattle ESPN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12730-Ag | Equine/Horse | Equine/Horse ESPN recombinant protein | Mammalian cell | Detail |
