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Target
sublocation: Introcelluar Protein.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
| Target ID |
GM-IP12715
|
| Target Name |
H4C2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8366
|
| Gene ID |
115945194 (Felis catus), 695323 (Macaca mulatta), 8366 (Homo sapiens)
|
| Target Alternative Names |
H4-16,H4/I,H4C1,H4C11,H4C12,H4C13,H4C14,H4C15,H4C16,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,H4FI,HIST1H4B,Histone H4,LOC115945194
|
| Uniprot Accession |
P62805
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSMMUG00000054127, ENSG00000278705
|
H4C2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8366 | Pre-made Human H4C2/H4/I/H4C1 siRNA oligo Duplex | 8366 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695323 | Pre-made Cynomolgus/Rhesus macaque H4C2 siRNA oligo Duplex | 695323 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo115945194 | Pre-made Cat/Feline LOC115945194 siRNA oligo Duplex | 115945194 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
H4C2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12715-Ab | Human | Anti-Human H4C2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12715-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque H4C2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12715-Ab | Cat/Feline | Anti-Cat/Feline H4C2 monoclonal antibody | mab | | Detail |
H4C2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12715-Ag | Human | Human H4C2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12715-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque H4C2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12715-Ag | Cat/Feline | Cat/Feline H4C2 recombinant protein | Mammalian cell | Detail |
