Explore DOCK8 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
| Target ID |
GM-IP12570
|
| Target Name |
DOCK8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
81704
|
| Gene ID |
100050677 (Equus caballus), 100295817 (Bos taurus), 101101598 (Felis catus), 476333 (Canis lupus familiaris)
499337 (Rattus norvegicus), 698081 (Macaca mulatta), 76088 (Mus musculus), 81704 (Homo sapiens)
|
| Target Alternative Names |
1200017A24Rik,5830472H07Rik,A130095G14Rik,DOCK8,Dedicator of cytokinesis protein 8,Dock8,HEL-205,HIES2,MRD2,ZIR8
|
| Uniprot Accession |
Q8C147,Q8NF50
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000011917, ENSBTAG00000002190, ENSCAFG00845001647, ENSMMUG00000016976, ENSMUSG00000052085, ENSG00000107099
|
DOCK8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo81704 | Pre-made Human DOCK8/MRD2/ZIR8 siRNA oligo Duplex | 81704 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo499337 | Pre-made Rat Dock8 siRNA oligo Duplex | 499337 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo76088 | Pre-made Mouse Dock8/1200017A24Rik/5830472H07Rik siRNA oligo Duplex | 76088 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698081 | Pre-made Cynomolgus/Rhesus macaque DOCK8 siRNA oligo Duplex | 698081 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101598 | Pre-made Cat/Feline DOCK8 siRNA oligo Duplex | 101101598 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476333 | Pre-made Dog/Canine DOCK8 siRNA oligo Duplex | 476333 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100295817 | Pre-made Bovines/Cattle DOCK8 siRNA oligo Duplex | 100295817 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050677 | Pre-made Equine/Horse DOCK8 siRNA oligo Duplex | 100050677 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DOCK8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12570-Ab | Human | Anti-Human DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12570-Ab | Rat | Anti-Rat DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12570-Ab | Mouse | Anti-Mouse DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12570-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12570-Ab | Cat/Feline | Anti-Cat/Feline DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12570-Ab | Dog/Canine | Anti-Dog/Canine DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12570-Ab | Bovines/Cattle | Anti-Bovines/Cattle DOCK8 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12570-Ab | Equine/Horse | Anti-Equine/Horse DOCK8 monoclonal antibody | mab | | Detail |
DOCK8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12570-Ag | Human | Human DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12570-Ag | Rat | Rat DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12570-Ag | Mouse | Mouse DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12570-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12570-Ag | Cat/Feline | Cat/Feline DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12570-Ag | Dog/Canine | Dog/Canine DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12570-Ag | Bovines/Cattle | Bovines/Cattle DOCK8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12570-Ag | Equine/Horse | Equine/Horse DOCK8 recombinant protein | Mammalian cell | Detail |
