Explore NPRL3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Predicted to enable GTPase activator activity. Involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Part of GATOR1 complex. Is active in lysosomal membrane. Implicated in familial focal epilepsy with variable foci 3. [provided by Alliance of Genome Resources, Feb 2025]
| Target ID |
GM-IP12526
|
| Target Name |
NPRL3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8131
|
| Gene ID |
100066396 (Equus caballus), 101097534 (Felis catus), 17168 (Mus musculus), 360505 (Rattus norvegicus) 534485 (Bos taurus), 611588 (Canis lupus familiaris), 722264 (Macaca mulatta), 8131 (Homo sapiens)
|
| Target Alternative Names |
-14 gene protein,Aag,Alpha-globin regulatory element-containing gene protein,C16ORF35,C16orf35,CGTHBA,FFEVF3,GATOR1 complex protein NPRL3,HS-26,HS-40,MARE,Mare,NPR3,NPRL3,Nitrogen permease regulator 3-like protein,Nprl3,Phg,Protein CGTHBA,Prox1,RGD1308665,RMD11,m(alpha)RE
|
| Uniprot Accession |
Q8VIJ8,Q12980
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000017195, ENSMUSG00000020289, ENSBTAG00000016564, ENSCAFG00845001178, ENSMMUG00000000590, ENSG00000103148
|
Pre-made viral vector of NPRL3 cDNA Clones/ORF Plasmid
NPRL3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8131 | Pre-made Human NPRL3/MARE/NPR3 siRNA oligo Duplex | 8131 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360505 | Pre-made Rat Nprl3/Mare/RGD1308665 siRNA oligo Duplex | 360505 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17168 | Pre-made Mouse Nprl3/Aag/Phg siRNA oligo Duplex | 17168 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722264 | Pre-made Cynomolgus/Rhesus macaque NPRL3 siRNA oligo Duplex | 722264 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097534 | Pre-made Cat/Feline NPRL3 siRNA oligo Duplex | 101097534 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611588 | Pre-made Dog/Canine NPRL3 siRNA oligo Duplex | 611588 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534485 | Pre-made Bovines/Cattle NPRL3/C16ORF35 siRNA oligo Duplex | 534485 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066396 | Pre-made Equine/Horse NPRL3 siRNA oligo Duplex | 100066396 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPRL3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12526-Ab | Human | Anti-Human NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12526-Ab | Rat | Anti-Rat NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12526-Ab | Mouse | Anti-Mouse NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12526-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12526-Ab | Cat/Feline | Anti-Cat/Feline NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12526-Ab | Dog/Canine | Anti-Dog/Canine NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12526-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPRL3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12526-Ab | Equine/Horse | Anti-Equine/Horse NPRL3 monoclonal antibody | mab | | Detail |
NPRL3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12526-Ag | Human | Human NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12526-Ag | Rat | Rat NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12526-Ag | Mouse | Mouse NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12526-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12526-Ag | Cat/Feline | Cat/Feline NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12526-Ag | Dog/Canine | Dog/Canine NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12526-Ag | Bovines/Cattle | Bovines/Cattle NPRL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12526-Ag | Equine/Horse | Equine/Horse NPRL3 recombinant protein | Mammalian cell | Detail |