Explore CEP290 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP12423
|
| Target Name |
CEP290
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
80184
|
| Gene ID |
100051209 (Equus caballus), 100113471 (Felis catus), 216274 (Mus musculus), 282707 (Bos taurus)
314787 (Rattus norvegicus), 482591 (Canis lupus familiaris), 708286 (Macaca mulatta), 80184 (Homo sapiens)
|
| Target Alternative Names |
3H11Ag,BBS14,Bardet-Biedl syndrome 14 protein,CEP290,CT87,Cancer/testis antigen 87 (CT87),Centrosomal protein of 290 kDa,Cep290,JBTS5,LCA10,MKS4,NPHP6,Nephrocystin-6,Nphp6,POC3,RGD1311640,SLSN6,Tumor antigen se2-2,b2b1454Clo,b2b1752Clo,rd16
|
| Uniprot Accession |
Q6A078,Q9TU23,O15078
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000020694, ENSMUSG00000019971, ENSBTAG00000018745, ENSCAFG00845017266, ENSMMUG00000015862, ENSG00000198707
|
CEP290 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo80184 | Pre-made Human CEP290/CT87/MKS4 siRNA oligo Duplex | 80184 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo314787 | Pre-made Rat Cep290/RGD1311640 siRNA oligo Duplex | 314787 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo216274 | Pre-made Mouse Cep290/Nphp6/b2b1454Clo siRNA oligo Duplex | 216274 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708286 | Pre-made Cynomolgus/Rhesus macaque CEP290 siRNA oligo Duplex | 708286 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100113471 | Pre-made Cat/Feline CEP290 siRNA oligo Duplex | 100113471 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482591 | Pre-made Dog/Canine CEP290 siRNA oligo Duplex | 482591 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282707 | Pre-made Bovines/Cattle CEP290 siRNA oligo Duplex | 282707 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051209 | Pre-made Equine/Horse CEP290 siRNA oligo Duplex | 100051209 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CEP290 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12423-Ab | Human | Anti-Human CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12423-Ab | Rat | Anti-Rat CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12423-Ab | Mouse | Anti-Mouse CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12423-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12423-Ab | Cat/Feline | Anti-Cat/Feline CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12423-Ab | Dog/Canine | Anti-Dog/Canine CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12423-Ab | Bovines/Cattle | Anti-Bovines/Cattle CEP290 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12423-Ab | Equine/Horse | Anti-Equine/Horse CEP290 monoclonal antibody | mab | | Detail |
CEP290 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12423-Ag | Human | Human CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12423-Ag | Rat | Rat CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12423-Ag | Mouse | Mouse CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12423-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12423-Ag | Cat/Feline | Cat/Feline CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12423-Ag | Dog/Canine | Dog/Canine CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12423-Ag | Bovines/Cattle | Bovines/Cattle CEP290 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12423-Ag | Equine/Horse | Equine/Horse CEP290 recombinant protein | Mammalian cell | Detail |
