MTHFD1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore MTHFD1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]

Target ID	GM-IP1217
Target Name	MTHFD1
Gene Group ldentifer （Target Gene ID in Homo species)	4522
Gene ID	100062154 (Equus caballus), 101086816 (Felis catus), 108156 (Mus musculus), 4522 (Homo sapiens) 480352 (Canis lupus familiaris), 534382 (Bos taurus), 64300 (Rattus norvegicus), 707059 (Macaca mulatta)
Target Alternative Names	C-1-tetrahydrofolate synthase,C1-THF synthase,CIMAH,Dcs,E430024A07Rik,Epididymis secretory sperm binding protein,MTHFC,MTHFD,MTHFD1,Mthfd,Mthfd1,cytoplasmic
Uniprot Accession	Q922D8,P11586,P27653
Protein Sub-location	Introcelluar Protein
Disease	cancer
Disease from KEGG	Metabolic pathways
Gene Ensembl	ENSECAG00000015580, ENSMUSG00000021048, ENSG00000100714, ENSCAFG00845002014, ENSBTAG00000009641, ENSMMUG00000001319

Pre-made viral vector of MTHFD1 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP003003	Human MTHFD1/CIMAH/MTHFC Lentivirus plasmid	NM_005956	4522	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP003003	Human MTHFD1/CIMAH/MTHFC Lentivirus particle	NM_005956	4522	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLPm005095	Mouse Mthfd1/Dcs/E430024A07Rik Lentivirus plasmid	NM_138745.2	108156	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm005095	Mouse Mthfd1/Dcs/E430024A07Rik Lentivirus particle	NM_138745.2	108156	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

MTHFD1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo4522	Pre-made Human MTHFD1/CIMAH/MTHFC siRNA oligo Duplex	4522	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo64300	Pre-made Rat Mthfd1 siRNA oligo Duplex	64300	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo108156	Pre-made Mouse Mthfd1/Dcs/Mthfd siRNA oligo Duplex	108156	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo707059	Pre-made Cynomolgus/Rhesus macaque MTHFD1 siRNA oligo Duplex	707059	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101086816	Pre-made Cat/Feline MTHFD1 siRNA oligo Duplex	101086816	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo480352	Pre-made Dog/Canine MTHFD1 siRNA oligo Duplex	480352	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo534382	Pre-made Bovines/Cattle MTHFD1 siRNA oligo Duplex	534382	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100062154	Pre-made Equine/Horse MTHFD1 siRNA oligo Duplex	100062154	Equine/Horse	In-vitro grade; in-vivo grade	Detail

MTHFD1 antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP1217-Ab	Human	Anti-Human MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-rg-IP1217-Ab	Rat	Anti-Rat MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-mg-IP1217-Ab	Mouse	Anti-Mouse MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-cynog-IP1217-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-felg-IP1217-Ab	Cat/Feline	Anti-Cat/Feline MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-cang-IP1217-Ab	Dog/Canine	Anti-Dog/Canine MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-bovg-IP1217-Ab	Bovines/Cattle	Anti-Bovines/Cattle MTHFD1 monoclonal antibody	mab	Detail
GM-Tg-equg-IP1217-Ab	Equine/Horse	Anti-Equine/Horse MTHFD1 monoclonal antibody	mab	Detail

MTHFD1 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP1217-Ag	Human	Human MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP1217-Ag	Rat	Rat MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP1217-Ag	Mouse	Mouse MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP1217-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP1217-Ag	Cat/Feline	Cat/Feline MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP1217-Ag	Dog/Canine	Dog/Canine MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP1217-Ag	Bovines/Cattle	Bovines/Cattle MTHFD1 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP1217-Ag	Equine/Horse	Equine/Horse MTHFD1 recombinant protein	Mammalian cell	Detail