Explore USP7 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
| Target ID |
GM-IP12063
|
| Target Name |
USP7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7874
|
| Gene ID |
100057484 (Equus caballus), 101088134 (Felis catus), 252870 (Mus musculus), 360471 (Rattus norvegicus) 479854 (Canis lupus familiaris), 514813 (Bos taurus), 714625 (Macaca mulatta), 7874 (Homo sapiens)
|
| Target Alternative Names |
2210010O09Rik,C16DELp13.2,DEL16P13.2,Deubiquitinating enzyme 7,HAFOUS,HAUSP,Hausp,Herpesvirus-associated ubiquitin-specific protease,TEF1,USP7,Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7,Usp7
|
| Uniprot Accession |
Q6A4J8,Q4VSI4,Q93009
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000009628, ENSMUSG00000022710, ENSCAFG00845013702, ENSBTAG00000005455, ENSMMUG00000047388, ENSG00000187555
|
Pre-made viral vector of USP7 cDNA Clones/ORF Plasmid
USP7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7874 | Pre-made Human USP7/TEF1/HAUSP siRNA oligo Duplex | 7874 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360471 | Pre-made Rat Usp7/Hausp siRNA oligo Duplex | 360471 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo252870 | Pre-made Mouse Usp7/Hausp/2210010O09Rik siRNA oligo Duplex | 252870 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714625 | Pre-made Cynomolgus/Rhesus macaque USP7 siRNA oligo Duplex | 714625 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088134 | Pre-made Cat/Feline USP7 siRNA oligo Duplex | 101088134 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479854 | Pre-made Dog/Canine USP7 siRNA oligo Duplex | 479854 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514813 | Pre-made Bovines/Cattle USP7 siRNA oligo Duplex | 514813 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057484 | Pre-made Equine/Horse USP7 siRNA oligo Duplex | 100057484 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
USP7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12063-Ab | Human | Anti-Human USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12063-Ab | Rat | Anti-Rat USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12063-Ab | Mouse | Anti-Mouse USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12063-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12063-Ab | Cat/Feline | Anti-Cat/Feline USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12063-Ab | Dog/Canine | Anti-Dog/Canine USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12063-Ab | Bovines/Cattle | Anti-Bovines/Cattle USP7 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12063-Ab | Equine/Horse | Anti-Equine/Horse USP7 monoclonal antibody | mab | | Detail |
USP7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12063-Ag | Human | Human USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12063-Ag | Rat | Rat USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12063-Ag | Mouse | Mouse USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12063-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12063-Ag | Cat/Feline | Cat/Feline USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12063-Ag | Dog/Canine | Dog/Canine USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12063-Ag | Bovines/Cattle | Bovines/Cattle USP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12063-Ag | Equine/Horse | Equine/Horse USP7 recombinant protein | Mammalian cell | Detail |