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Target
sublocation: Introcelluar Protein.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP11889
|
| Target Name |
UBE1L/UBA7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7318
|
| Gene ID |
100052809 (Equus caballus), 101088821 (Felis catus), 301000 (Rattus norvegicus), 497204 (Bos taurus) 608118 (Canis lupus familiaris), 704875 (Macaca mulatta), 7318 (Homo sapiens), 74153 (Mus musculus)
|
| Target Alternative Names |
1300004C08Rik,D8,UBA1B,UBA7,UBE1L,UBE2,UBE7,Uba7,Ube1l,Ubiquitin-activating enzyme 7,Ubiquitin-activating enzyme E1 homolog,Ubiquitin-like modifier-activating enzyme 7
|
| Uniprot Accession |
P41226,Q9DBK7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000019670, ENSBTAG00000012335, ENSCAFG00845024488, ENSMMUG00000020980, ENSG00000182179, ENSMUSG00000032596
|
Pre-made viral vector of UBE1L/UBA7 cDNA Clones/ORF Plasmid
UBE1L/UBA7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7318 | Pre-made Human UBA7/D8/UBE2 siRNA oligo Duplex | 7318 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301000 | Pre-made Rat Uba7/Ube1l siRNA oligo Duplex | 301000 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74153 | Pre-made Mouse Uba7/Ube1l/1300004C08Rik siRNA oligo Duplex | 74153 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704875 | Pre-made Cynomolgus/Rhesus macaque UBA7 siRNA oligo Duplex | 704875 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088821 | Pre-made Cat/Feline UBA7/UBE1L siRNA oligo Duplex | 101088821 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608118 | Pre-made Dog/Canine UBA7/UBE1L siRNA oligo Duplex | 608118 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497204 | Pre-made Bovines/Cattle UBA7/UBE1L siRNA oligo Duplex | 497204 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052809 | Pre-made Equine/Horse UBA7 siRNA oligo Duplex | 100052809 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
UBE1L/UBA7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11889-Ab | Human | Anti-Human UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11889-Ab | Rat | Anti-Rat UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11889-Ab | Mouse | Anti-Mouse UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11889-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11889-Ab | Cat/Feline | Anti-Cat/Feline UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11889-Ab | Dog/Canine | Anti-Dog/Canine UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11889-Ab | Bovines/Cattle | Anti-Bovines/Cattle UBE1L/UBA7 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11889-Ab | Equine/Horse | Anti-Equine/Horse UBE1L/UBA7 monoclonal antibody | mab | | Detail |
UBE1L/UBA7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11889-Ag | Human | Human UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11889-Ag | Rat | Rat UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11889-Ag | Mouse | Mouse UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11889-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11889-Ag | Cat/Feline | Cat/Feline UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11889-Ag | Dog/Canine | Dog/Canine UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11889-Ag | Bovines/Cattle | Bovines/Cattle UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11889-Ag | Equine/Horse | Equine/Horse UBE1L/UBA7 recombinant protein | Mammalian cell | Detail |