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Target
sublocation: Introcelluar Protein.
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
| Target ID |
GM-IP11712
|
| Target Name |
TOP3A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7156
|
| Gene ID |
100051666 (Equus caballus), 101086515 (Felis catus), 21975 (Mus musculus), 303194 (Rattus norvegicus)
489537 (Canis lupus familiaris), 527411 (Bos taurus), 700830 (Macaca mulatta), 7156 (Homo sapiens)
|
| Target Alternative Names |
DNA topoisomerase 3-alpha,DNA topoisomerase III alpha,MGRISCE2,PEOB5,TOP3,TOP3A,Top3a,ZGRF7
|
| Uniprot Accession |
O70157,Q13472
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000016343, ENSMUSG00000002814, ENSCAFG00845020363, ENSBTAG00000017087, ENSMMUG00000013533, ENSG00000177302
|
TOP3A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7156 | Pre-made Human TOP3A/TOP3/PEOB5 siRNA oligo Duplex | 7156 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo303194 | Pre-made Rat Top3a siRNA oligo Duplex | 303194 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21975 | Pre-made Mouse Top3a siRNA oligo Duplex | 21975 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700830 | Pre-made Cynomolgus/Rhesus macaque TOP3A siRNA oligo Duplex | 700830 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086515 | Pre-made Cat/Feline TOP3A siRNA oligo Duplex | 101086515 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489537 | Pre-made Dog/Canine TOP3A siRNA oligo Duplex | 489537 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527411 | Pre-made Bovines/Cattle TOP3A siRNA oligo Duplex | 527411 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051666 | Pre-made Equine/Horse TOP3A siRNA oligo Duplex | 100051666 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TOP3A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11712-Ab | Human | Anti-Human TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11712-Ab | Rat | Anti-Rat TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11712-Ab | Mouse | Anti-Mouse TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11712-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11712-Ab | Cat/Feline | Anti-Cat/Feline TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11712-Ab | Dog/Canine | Anti-Dog/Canine TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11712-Ab | Bovines/Cattle | Anti-Bovines/Cattle TOP3A monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11712-Ab | Equine/Horse | Anti-Equine/Horse TOP3A monoclonal antibody | mab | | Detail |
TOP3A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11712-Ag | Human | Human TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11712-Ag | Rat | Rat TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11712-Ag | Mouse | Mouse TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11712-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11712-Ag | Cat/Feline | Cat/Feline TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11712-Ag | Dog/Canine | Dog/Canine TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11712-Ag | Bovines/Cattle | Bovines/Cattle TOP3A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11712-Ag | Equine/Horse | Equine/Horse TOP3A recombinant protein | Mammalian cell | Detail |
