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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012]
| Target ID |
GM-IP11696
|
| Target Name |
TK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7084
|
| Gene ID |
100065312 (Equus caballus), 101085008 (Felis catus), 291824 (Rattus norvegicus), 57813 (Mus musculus)
611387 (Canis lupus familiaris), 615457 (Bos taurus), 693544 (Macaca mulatta), 7084 (Homo sapiens)
|
| Target Alternative Names |
2'-deoxyuridine kinase TK2,Deoxycytidine kinase TK2,MTDPS2,MTTK,Mt-TK,PEOB3,SCA31,TK2,TK2-EXT,Thymidine kinase 2,Tk2,mitochondrial,mt-TK
|
| Uniprot Accession |
Q9R088,O00142
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000007170, ENSMUSG00000035824, ENSCAFG00845011863, ENSBTAG00000005152, ENSMMUG00000000029, ENSG00000166548
|
Pre-made viral vector of TK2 cDNA Clones/ORF Plasmid
TK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7084 | Pre-made Human TK2/MTTK/PEOB3 siRNA oligo Duplex | 7084 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo291824 | Pre-made Rat Tk2 siRNA oligo Duplex | 291824 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo57813 | Pre-made Mouse Tk2/mt-TK siRNA oligo Duplex | 57813 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693544 | Pre-made Cynomolgus/Rhesus macaque TK2 siRNA oligo Duplex | 693544 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085008 | Pre-made Cat/Feline TK2 siRNA oligo Duplex | 101085008 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611387 | Pre-made Dog/Canine TK2 siRNA oligo Duplex | 611387 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615457 | Pre-made Bovines/Cattle TK2 siRNA oligo Duplex | 615457 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065312 | Pre-made Equine/Horse TK2 siRNA oligo Duplex | 100065312 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11696-Ab | Human | Anti-Human TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11696-Ab | Rat | Anti-Rat TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11696-Ab | Mouse | Anti-Mouse TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11696-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11696-Ab | Cat/Feline | Anti-Cat/Feline TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11696-Ab | Dog/Canine | Anti-Dog/Canine TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11696-Ab | Bovines/Cattle | Anti-Bovines/Cattle TK2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11696-Ab | Equine/Horse | Anti-Equine/Horse TK2 monoclonal antibody | mab | | Detail |
TK2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11696-Ag | Human | Human TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11696-Ag | Rat | Rat TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11696-Ag | Mouse | Mouse TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11696-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11696-Ag | Cat/Feline | Cat/Feline TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11696-Ag | Dog/Canine | Dog/Canine TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11696-Ag | Bovines/Cattle | Bovines/Cattle TK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11696-Ag | Equine/Horse | Equine/Horse TK2 recombinant protein | Mammalian cell | Detail |
